Optimization of Black Blood CINE for Mobile Plaque

Abstract

For examining carotid plaque, black blood (BB) magnetic resonance (MR) imaging can diagnose plaque components based on MR signals. Dynamic images for evaluating the mobility of carotid plaque may also be useful as an adjunct to the diagnosis of carotid plaque. The aim of this study was to find optimal parameters for dynamic images using the black blood technique (BB CINE). All experiments were acquired using electrocardiographically (ECG)-gated T1 turbo field echo (T1 TFE) combined with the regional saturation technique (REST) and improved motion-sensitized driven equilibrium (iMSDE) at 1.5 tesla (T). The following parameters were investigated. (1) Four fat suppression techniques: spectral presaturation with IR (SPIR), the principle of selective excitation technique (PROSET) with a binomial excitation of 1-1 (PROSET1-1), PROSET1-2-1 and PROSET1-3-3-1; (2) TFE factors 1 and 2; and (3) flow velocity encoding (venc) of 1, 3, 5, 10 and 15 cm/s for iMSDE. The results showed the optimal parameters for BB CINE to be PROSET1-2-1, TFE factor 2, and flow venc of 3-5 cm/s for iMSDE.