2024
DOI: 10.1248/yakushi.24-00149
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Optimization of Drug Administration in Special Populations Focusing on Drug Distribution

Hirotaka Miyamoto

Abstract: Patients with special backgrounds such as organ dysfunction, elderly individuals, children, and pregnant or nursing women in whom the pharmacokinetics of an agent are expected to differ from those observed in the general patient population, are referred to as special populations. Administration of drug therapy to these patients warrants close attention to and knowledge of altered pharmacokinetics to design appropriate personalized dosing regimens. In this study, we investigated the effects of hypothermia and r… Show more

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