Optimization of low-dose scan parameters in dual-energy computed tomography for displaying the anterior cruciate ligament

Bai, Rui; Li, Xiangdong; Li, Rurui; He, Xiaohua; Wen, Zhibo

doi:10.1177/0300060520927874

Cited by 4 publications

(2 citation statements)

References 11 publications

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“…Fickert (10) and Peltola et al (11) also successively reported the diagnosis of a cruciate ligament injury on piglet animal models and for patients using DECT. Our previous study (12) found a new potential sign of DECT in diagnosing ACL injury, i.e. diminution sign-on dual-energy color mapping, which preliminarily proved the feasibility of this method.…”

Section: Introductionmentioning

confidence: 70%

A basic study for the molecular imaging of dual-energy CT in diagnosing anterior cruciate ligament injury of knee joint

Bai¹,

Huang³

2022

Acta Radiol

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Background Anterior cruciate ligament (ACL) injury is a common disease in clinical practice that seriously affects the daily life of patients. Purpose To explore the molecular imaging basis of “diminution sign on dual-energy colour mapping” for the diagnosis of ACL injury by dual-energy computed tomography (DECT). Material and Methods The hydroxylysine and hydroxyproline reagents were prepared in different concentrations. The grouping was shown as follows: a simple concentration change group of an amino acid (group 1/2); a mixed solution group with the concentration increasing synchronously (group 3); a mixed solution group with the concentration reverse increasing and decreasing (group 4); and a mixed solution group that fix one amino acid with increasing concentration of the other (group 5/6). The samples were scanned by DECT. The solution CT value and image signal-to-noise ratio were analyzed. Results In group 1/2, the brightness of the dual-energy color mapping of each test tube solution and the CT value increased with increasing the concentration of amino acid. In group 6, there was no significant change in the brightness and brilliance of the dual-energy color mapping and the CT value. The remaining three groups showed an increase in the brightness and brilliance of the dual-energy color mapping and the CT value, and this increase was positively associated with the hydroxylysine concentration. Conclusion The dual-energy staining of the DECT imaging in “tendon” mode is related to hydroxylysine and hydroxyproline. Moreover, the degree of dual-energy color mapping is positively correlated with the change of CT value.

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Section: Introductionmentioning

confidence: 70%

A basic study for the molecular imaging of dual-energy CT in diagnosing anterior cruciate ligament injury of knee joint

Bai¹,

Huang³

2022

Acta Radiol

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“… 26 Dual‐energy CT has a growing role in diagnosing gout and bone marrow edema. Also, Bai et al 27 displayed the anterior cruciate ligament using dual‐energy CT. In the present study, two components of CC ligament could be distinctly seen on the color‐coding dual‐energy CT images, and we proved in another study that CC ligament was best shown at 40 keV.…”

Section: Discussionmentioning

confidence: 99%

A Novel and Open Classification Emphasizing on Osteoligamentous Complex for Distal Clavicle Fractures

Han

Dong

et al. 2022

Orthopaedic Surgery

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ObjectiveCurrent X‐ray‐based classification methods cannot describe all distal clavicle fracture (DCF) patterns, especially the osteoligamentous injury pattern of DCFs. We aimed to develop a novel classification based on the osteoligamentous injury pattern of the DCFs and investigated its reliability.MethodsAll DCFs from January 2017 to January 2022 were respectively screened and 45 cases (mean age 20–78; male 31, female 14) met the including criteria and were enrolled. Based on their Zanca view X‐ray radiograph and three‐dimensional CT construction images, we analyzed the osteoligamentous injury pattern of each case, particularly the acromioclavicular (AC) and coracoclavicular ligaments and their bone attachment. Then we developed a novel classification method, five types in total, sorting all DCFs according to their lesion manifestations of osteoligamentous complex. Also, we investigated the inter‐ and intra‐observer reliability using kappa value.ResultsA novel classification method for DCF was developed, manifesting the avulsion or rupture of conoid and trapezoid ligaments, and involvement of AC joint. Forty‐five cases of DCFs were included in this study. Among them, 11 (24.4%) were Type 1 fracture, three (6.7%) cases were Type 2, six cases (13.3%) were Type 3, 21 (46.7%) were Type 4, four (8.9%) were Type 5. Kappa values for inter‐observer agreement were 0.57 after first evaluation and 0.61 after second evaluation. Intra‐observer agreement was 0.72 for experienced shoulder specialist and 0.63 for radiologist.ConclusionThis new classification method is reliable to use, supplementary to current classification systems, and emphasizes on the osteoligamentous complex injury when opting for the treatment.

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Diagnostic performance of dual-energy computed tomography in detecting anterior cruciate ligament injuries: a systematic review and meta-analysis

Valizadeh,

Jannatdoust,

Pahlevan-Fallahy

et al. 2024

Skeletal Radiol

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Objective Anterior cruciate ligament (ACL) injuries are common and lead to significant physical limitations. While MRI is the diagnostic gold standard, its use is restricted in acute trauma cases due to contraindications and longer imaging times. Dual-energy computed tomography (DECT) has emerged as a potential alternative. This meta-analysis evaluates the diagnostic accuracy of DECT for ACL injuries. Materials and methods Following PRISMA guidelines, a comprehensive literature search was conducted using PubMed, Web of Science, Scopus, and Embase for studies published up to June 2024. Studies that provided diagnostic accuracy data for DECT in ACL ruptures were included. Metrics of diagnostic accuracy were aggregated using a bivariate random effects model. Results The meta-analysis, which included five studies with a total of 191 patients, found that DECT had a pooled sensitivity of 88.1% (95% CI, 78.0–93.9%) and a specificity of 82.0% (95% CI, 62.0–92.7%) for diagnosing ACL ruptures, with an AUC of 0.92 (95% CI, 0.72–0.96). For complete ruptures, sensitivity was 83.2% (95% CI, 68.2–92.0%), and specificity was 94.9% (95% CI, 92.2–96.7%), with an AUC of 0.96 (95% CI, 0.81–0.98). In acute/subacute settings, sensitivity was 89.4% (95% CI, 76.8–95.6%), and specificity was 82.1% (95% CI, 56.2–94.2%), with an AUC of 0.93 (95% CI, 0.71–0.97). Conclusion Our findings suggest that DECT is a valuable diagnostic tool for ACL injuries, particularly as an adjunct or alternative when MRI is unavailable or contraindicated, enabling timely and accurate diagnosis.

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Optimization of low-dose scan parameters in dual-energy computed tomography for displaying the anterior cruciate ligament

Cited by 4 publications

References 11 publications

A basic study for the molecular imaging of dual-energy CT in diagnosing anterior cruciate ligament injury of knee joint

A basic study for the molecular imaging of dual-energy CT in diagnosing anterior cruciate ligament injury of knee joint

A Novel and Open Classification Emphasizing on Osteoligamentous Complex for Distal Clavicle Fractures

Diagnostic performance of dual-energy computed tomography in detecting anterior cruciate ligament injuries: a systematic review and meta-analysis

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