2012
DOI: 10.1109/tmag.2012.2197601
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Optimization of Magnetic Nanoparticles for Magnetic Particle Imaging

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Cited by 65 publications
(49 citation statements)
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“…The FeraSpin R particles are carboxydextran coated multicore particles, i.e. the multi-core particles consist of clusters composed of smaller nanocrystals of about 5-8 nm [10,11]. The multi-core particles exhibit a size distribution with the smallest one comprising only one nanocrystal per multi-core particle and the larger ones containing multiple nanocrystals per multi-core particle.…”
Section: Methodsmentioning
confidence: 99%
“…The FeraSpin R particles are carboxydextran coated multicore particles, i.e. the multi-core particles consist of clusters composed of smaller nanocrystals of about 5-8 nm [10,11]. The multi-core particles exhibit a size distribution with the smallest one comprising only one nanocrystal per multi-core particle and the larger ones containing multiple nanocrystals per multi-core particle.…”
Section: Methodsmentioning
confidence: 99%
“…Therefore, the isolation of this large sized particle population responsible for the high MPI signal is of great interest. Several attempts were made to separate Resovist s magnetically [5,6] and characterize the obtained fractions with regard to MPI performance [7][8][9]. Furthermore, asymmetric flow field-flow fractionations (A4F) were performed to gain insight into the distribution of hydrodynamic sizes of Resovist s as this method gently produces fractions of narrow hydrodynamic size distribution and permits highly reproducible and accurate size evaluations [4,10,11].…”
Section: Introductionmentioning
confidence: 99%
“…[33][34][35] Resovist is a 60 nm carboxydextrancoated SPION with superior cellular uptake properties [36][37][38] and a higher heating capability, or calculated intrinsic loss power, than other SPIONs, 39 such as clinically available Endorem (sample VII). 40 However, since Resovist is now commercially unavailable, Feraspin R, a closely related SPION formula with very similar properties to Resovist, 41 was employed to study the feasibility of using MFH to enhance CTL killing of HIV-infected cells by two distinct mechanisms. The thermotherapeutic heat generated in cloned, Feraspin R-loaded autologous patient CTLs through alternating magnetic field exposure could either lead to the death of CTL-bound antigen-expressing target cells through direct thermal ablation or enhance their cytolytic CTL activity when these cells are adoptively transferred back into the patient.…”
Section: Introductionmentioning
confidence: 99%