In this Letter, we introduce a concept to produce high-resolution, highly integrable biosensing devices. Our idea exploits the highly absorbing modes in multilayered metamaterials to maximize the transverse magneto-optical Kerr effect (TMOKE). Results are discussed in the context of dielectric uniaxial (εeff,∥εeff,⊥>0) and hyperbolic metamaterial (εeff,∥εeff,⊥<0) regimes. For applications in gas sensing, we obtained sensitivities of S = 46.02 deg/RIU and S = 73.91 deg/RIU when considering the system working in the uniaxial and hyperbolic regimes, respectively, with figures of merit (resolution) in the order of 310 or higher. On the contrary, when considering the system for biosensing applications (incidence from an aqueous medium), we observed that the proposed mechanism can only be successfully used in the uniaxial regime, where a sensitivity of 56.87 deg/RIU was obtained.