Optimization of microelectrode array geometry in a rectangular flow channel detector

Microelectrode Arrays with Overlapped Diffusion Layers as Electroanalytical Detectors: Theory and Basic Applications

“…In the eighties and nineties of the last century a series of individually polarizable electrodes started to be used for this type of analysis [ 66 – 68 ]. However, there was no diffusion layer overlapping due to the large distance between each other, therefore they were substituted by microelectrodes with close geometrical arrangement of individually addressable segments [ 69 , 70 ]. The simplest type of this kind of microelectrode arrays was the double rectangular electrode (DRE) [ 71 ].…”

Design rule for optimization of microelectrodes used in electric cell-substrate impedance sensing (ECIS)

“…Researchers have performed experiments to optimize the electrode designs for various applications. Fosdick and Anderson (1986) optimized the geometry of a microelectrode array flow detector; with respect to amperometric response; and Min et al (2004) investigated geometric parameters (i.e. electrode height, material, gap size, and electrode width) of interdigitated ultramicroelectrode arrays (IDUAs) to optimize oxidation and reduction reactions of ferro/ferrihexacyanide.…”

Mathematical modeling of interdigitated electrode arrays in finite electrochemical cells

“…When using photolithography and transparency sheet masks, the electrodes are constrained by the resolution of the transparency sheet mask, which can generate features between 20 µm-50 µm when using a printer operating at 3380 dpi-5080 dpi [14,15]. Therefore, the ratio between the 'height of the cell' and the center-to-center 'separation of the electrodes' obtained using these techniques is clearly finite and may vary between ∼ 0.01 − 10.Electrochemical applications [12,13,[16][17][18][19][20][21] and research through simulations [22][23][24][25] have been reported for IDAE in continuous flow microfluidic devices, which take into account the height of the channel and verify the dependence of the current with respect to the flow rate. Despite these researches, it is known from previous reports that signal amplification by redox cycling increases with decreasing flow rate, being most effective with stagnant solutions [21,26,27].…”

“…Electrochemical applications [12,13,[16][17][18][19][20][21] and research through simulations [22][23][24][25] have been reported for IDAE in continuous flow microfluidic devices, which take into account the height of the channel and verify the dependence of the current with respect to the flow rate. Despite these researches, it is known from previous reports that signal amplification by redox cycling increases with decreasing flow rate, being most effective with stagnant solutions [21,26,27].…”