Optimization of microwave‐assisted extraction of anthocyanins in red cabbage by response surface methodology

Yiğit, Ünzile; Yolaçaner, Elif Turabi; Hamzalıoğlu, Aytül; Gökmen, Vural

doi:10.1111/jfpp.16120

Cited by 13 publications

(6 citation statements)

References 45 publications

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“…Several studies have shown that MAE has some advantages compared to conventional extraction [ 58 , 59 , 60 , 61 , 62 ]. These studies claim that MAE lasts for less time and consumes less solvent [ 58 ], and allows higher extraction yields than a conventional extraction [ 41 , 56 ]. In addition, it is an energy-saving method due to its short processing time.…”

Section: Extraction Methods Used To Extract Anthocyaninsmentioning

confidence: 99%

“…Despite the need to control and optimize the thermal conditions under which MAE is carried out to avoid a negative effect on the antioxidant properties and the color of the extract obtained, several studies have been carried out to explore the possible application of this technique in the extraction of anthocyanins [Table 2]. Several studies have shown that MAE has some advantages compared to conventional extraction [58][59][60][61][62]. These studies claim that MAE lasts for less time and consumes less solvent [58], and allows higher extraction yields than a conventional extraction [41,56].…”

Section: Microwave-assisted Extraction (Mae)mentioning

confidence: 99%

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Up-To-Date Analysis of the Extraction Methods for Anthocyanins: Principles of the Techniques, Optimization, Technical Progress, and Industrial Application

Tena

Asuero

2022

Antioxidants

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Nowadays, food industries are concerned about satisfying legal requirements related to waste policy and environmental protection. In addition, they take steps to ensure food safety and quality products that have high nutritional properties. Anthocyanins are considered high added-value compounds due to their sensory qualities, colors, and nutritional properties; they are considered bioactive ingredients. They are found in high concentrations in many by-products across the food industry. Thus, the non-conventional extraction techniques presented here are useful in satisfying the current food industry requirements. However, selecting more convenient extraction techniques is not easy. Multiple factors are implicated in the decision. In this review, we compile the most recent applications (since 2015) used to extract anthocyanins from different natural matrices, via conventional and non-conventional extraction techniques. We analyze the main advantages and disadvantages of anthocyanin extraction techniques from different natural matrices and discuss the selection criteria for sustainability of the processes. We present an up-to-date analysis of the principles of the techniques and an optimization of the extraction conditions, technical progress, and industrial applications. Finally, we provide a critical comparison between these techniques and some recommendations, to select and optimize the techniques for industrial applications.

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Section: Extraction Methods Used To Extract Anthocyaninsmentioning

confidence: 99%

Section: Microwave-assisted Extraction (Mae)mentioning

confidence: 99%

Up-To-Date Analysis of the Extraction Methods for Anthocyanins: Principles of the Techniques, Optimization, Technical Progress, and Industrial Application

Tena

Asuero

2022

Antioxidants

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“…However, the sample matrix and solvent have more surface area in contact with one another, which boosts extraction yield. [ 20 21 ]…”

Section: Discussionmentioning

confidence: 99%

Optimization of microwave-assisted extraction on polyphenol metabolite from Eleutherine bulbosa (Mill.) urb. bulbs using response surface methodology

Ahmad

Narsa²,

Ramadhani³

et al. 2023

Journal of Advanced Pharmaceutical Technology &Amp; Research

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Eleutherine bulbosa bulbs, an endemic plant in Indonesia, have enormous potential as raw materials for pharmaceutical products. Therefore, it is necessary to strengthen and develop extraction methods that are easy, rapid, and efficient to enrich targeted secondary metabolites. This study aims to optimize the microwave-assisted extraction (MAE) method conditions for polyphenol metabolite from E. bulbosa bulbs. The MAE method (with different conditions) was applied to extract total polyphenol content (TPC) from E. bulbosa bulbs. TPC values were determined using a 96-well microplate reader spectrophotometry method and Folin–Ciocalteu reagent. The variables of MAE, as an experimental design-independent variable, were involved. The MAE method condition was optimized using response surface methodology (RSM) and Box–Behnken design based on the TPC value. The MAE condition was optimized with 60% ethanol, sample–solvent ratio of 1:10 g/mL, and 50% Watts of microwave power for 10 min. The quadratic regression analysis was achieved to predict the TPC value using the equation: TPC value = 28.63–5.545A +2.211B –0.741C +1.995D – 4.045AB +0.856AC –7.541BC +1.961CD –8.342A 2 –0.071B 2 +1.840C 2 –1.535D 2 . For the scale-up confirmation test, a 50-g sample was used to prove the validity of the equation to predict the TPC value, yielding 35.33 ± 2.13 mg gallic acid equivalent/g samples. The optimum of the MAE condition recommended based on the results of RSM analysis can be applied directly to the enrichment of polyphenols metabolite constituent of E. bulbosa easily, cheaply, quickly, and efficiently.

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“…Their results showed that the optimal extraction process parameters were obtained as follows: extraction time of 4 min, microwave power of 200 W, extraction temperature of 40 °C, and solid-to-liquid ratio of 1:20 g/mL. The yield of anthocyanins was 241.20 mg/L under these parameters [ 30 ]. Anthocyanins from red bean seed coats were extracted via MAE, and the extraction process was optimized using RSM.…”

Section: Anthocyanin Extraction Methodsmentioning

confidence: 99%

Research Progress on the Extraction and Purification of Anthocyanins and Their Interactions with Proteins

Xue,

Zha,

Tang

et al. 2024

Molecules

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Anthocyanins, as the most critical water-soluble pigments in nature, are widely present in roots, stems, leaves, flowers, fruits, and fruit peels. Many studies have indicated that anthocyanins exhibit various biological activities including antioxidant, anti-inflammatory, anti-tumor, hypoglycemic, vision protection, and anti-aging. Hence, anthocyanins are widely used in food, medicine, and cosmetics. The green and efficient extraction and purification of anthocyanins are an important prerequisite for their further development and utilization. However, the poor stability and low bioavailability of anthocyanins limit their application. Protein, one of the three essential nutrients for the human body, has good biocompatibility and biodegradability. Proteins are commonly used in food processing, but their functional properties need to be improved. Notably, anthocyanins can interact with proteins through covalent and non-covalent means during food processing, which can effectively improve the stability of anthocyanins and enhance their bioavailability. Moreover, the interactions between proteins and anthocyanins can also improve the functional characteristics and enhance the nutritional quality of proteins. Hence, this article systematically reviews the extraction and purification methods for anthocyanins. Moreover, this review also systematically summarizes the effect of the interactions between anthocyanins and proteins on the bioavailability of anthocyanins and their impact on protein properties. Furthermore, we also introduce the application of the interaction between anthocyanins and proteins. The findings can provide a theoretical reference for the application of anthocyanins and proteins in food deep processing.

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Optimization of microwave‐assisted extraction of anthocyanins in red cabbage by response surface methodology

Cited by 13 publications

References 45 publications

Up-To-Date Analysis of the Extraction Methods for Anthocyanins: Principles of the Techniques, Optimization, Technical Progress, and Industrial Application

Up-To-Date Analysis of the Extraction Methods for Anthocyanins: Principles of the Techniques, Optimization, Technical Progress, and Industrial Application

Optimization of microwave-assisted extraction on polyphenol metabolite from Eleutherine bulbosa (Mill.) urb. bulbs using response surface methodology

Research Progress on the Extraction and Purification of Anthocyanins and Their Interactions with Proteins

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