Most silica photonic crystal fibers have limited spectral broadening in the infrared region, making them less than ideal in terms of technological applications. In this work, we propose a new Ge20Sb5Se75 chalcogenide octagonal photonic crystal fiber that provides diverse dispersions with all-normal and anomalous regimes and multiple zero-dispersion wavelengths. The nonlinear properties are investigated over a wide wavelength range up to 14 µm by numerically solving Maxwell's wave equations using Lumerical Mode Solutions software. The full-vector finite-difference eigenmode method minimizes the losses so that low confinement losses in the short-wavelength region of 1 − 6 µm are found and nonlinear coefficients as high as thousands of W−1.km−1 are achieved. Three fibers with an all-normal dispersion profile and anomalous dispersion with one or three zero dispersion wavelengths are proposed for supercontinuum generation. The fibers provide small dispersion values of −0.88, 0.08, and 1.646 ps/(nm.km) at suitable pump wavelengths. Furthermore, the very small confinement loss of approximately 10−5 to 10−11 dB/m is the outstanding advantage of these optical fibers. A broadband spectrum with low input power is expected as a result of the proposed fiber-based supercontinuum generation.