Optimization of power used in liver cancer microwave therapy by injection of Magnetic Nanoparticles (MNPs)

Minbashi, Mehran; Kordbacheh, Amirhossein Ahmadkhan; Ghobadi, Arash; Tuchin, Valery V.

doi:10.1016/j.compbiomed.2020.103741

Cited by 17 publications

(9 citation statements)

References 54 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…One way to enhance MWA efficiency is nanoparticle-based therapeutic approach, such as magnetic nanoparticles and liposomes, which can be used as heat sources and reduce input power significantly to produce a similar ablation [122][123][124]. Another is to optimize the internal structure of the antenna to improve its power transmission efficiency, making more energy deposited into the tissue.…”

Section: Designs To Improve the Efficiencymentioning

confidence: 99%

A review of antenna designs for percutaneous microwave ablation

et al. 2021

View full text Add to dashboard Cite

Microwave (MW) antenna is a key element in microwave ablation (MWA) treatments as the means that energy is delivered in a focused manner to the tumor and its surrounding area. The energy delivered results in a rise in temperature to a lethal level, resulting in cell death in the ablation zone. The delivery of energy and hence the success of MWA is closely dependent on the structure of the antennas. Therefore, three design criteria, such as expected ablation zone pattern, efficiency of energy delivery, and minimization of the diameter of the antennas have been the focus along the evolution of the MW antenna. To further improve the performance of MWA in the treatment of various tumors through inventing novel antennas, this article reviews the state-of-the-art and summarizes the development of MW antenna designs regarding the three design criteria.

show abstract

Section: Designs To Improve the Efficiencymentioning

confidence: 99%

A review of antenna designs for percutaneous microwave ablation

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Here it was noted that the presence of the magnetic NPs allowed a lower power input of MW radiation to achieve the desired level of hyperthermia. 82 Iron oxide composite NPs have also been identified as candidates for microwave-controlled drug release, 83 further demonstrating their potential in both contrast and therapeutics.…”

Section: Nanoparticle Enhanced Microwave Hyperthermiamentioning

confidence: 99%

Nanomaterials responding to microwaves: an emerging field for imaging and therapy

et al. 2021

View full text Add to dashboard Cite

show abstract

“…In 2020, the effects of microwave power radiation of 2.45 GHz with between 35 W and 90 W on magnetic nanoparticle injected liver cancer tissue have been investigated by Minbashi et al Their results indicate that the MNPs injected cancerous tissue require less microwave power than cancerous tissue not injected. With an optimization study to identify the input power sufficient for ablation, it was observed that the required microwave power for ablation is 35 W instead of 90 W [16]. In the same year, Salamon et al have developed phantoms based on denatured chicken white protein embedding superparamagnetic iron oxide nanoparticles that were locally heated up to 70 °C under alternating magnetic field excitation with a field amplitude and frequency of 12 mT and a power of 25 kHz.…”

Section: Introductionmentioning

confidence: 99%

Investigation of Electrical Properties of Iron Oxide Nanoparticles Bonded with Ionic Solutions for Microwave Ablation Systems

Murat¹,

Kaya²,

Keseli³

et al. 2023

IJEMD-Engr

View full text Add to dashboard Cite

Microwave ablation (MWA) is known as an alternative therapy to surgery to treat tumors. However, MWA-based therapy requires advanced approaches in order to prevent causing damage to healthy tissue around the tumor and selectively target the desired area. Nanoparticles are considered promising tools in biomedicine to fulfill these requirements. This study was carried out in order to analyze the effect of iron oxide nanoparticles on the temperature increment during radiofrequency ablation therapy with different salt solutions including NaCl and KCl as inorganics, and pictic acid (IP6) as organic. Iron oxide nanoparticles (IONPs) with a size of 42 nm, a surface area of 77.1 m2/g, and a high magnetic field absorption capability of 0.893 A/m were synthesized. According to the results, the magnetic nanoparticles from the IP6 solution have a higher number of charges in the recipes, and also, they reacted faster than the commercially available salt solutions like KCl and NaCl since six NaSO3 molecules are in the content of the IP6. With the absorption of 5-20 % higher electromagnetic power density depending on the content of salt solution with IP6 leads to 7-10 % temperature increase under 59 W microwave input power with 2 minutes exposure. This results show that the novelty of a dipole-dipole interaction of organic IP6 with IONPs improve the ablation performance.

show abstract

Optimization of power used in liver cancer microwave therapy by injection of Magnetic Nanoparticles (MNPs)

Cited by 17 publications

References 54 publications

A review of antenna designs for percutaneous microwave ablation

A review of antenna designs for percutaneous microwave ablation

Nanomaterials responding to microwaves: an emerging field for imaging and therapy

Investigation of Electrical Properties of Iron Oxide Nanoparticles Bonded with Ionic Solutions for Microwave Ablation Systems

Contact Info

Product

Resources

About