2017
DOI: 10.1016/j.seppur.2016.10.013
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Optimization of pressure-enhanced solid-liquid extraction of flavonoids from Flos Sophorae and evaluation of their antioxidant activity

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Cited by 47 publications
(23 citation statements)
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“…These results could be explained by Xi and Luo [82], who found that increasing the pressure has positive effect on the solvent viscosity, diffusion and surface tension, thus increases solubility of the natural compounds, but further increase in the pressure can damage these compounds. Xi and Yan [81] had also shown that higher yield of flavonoids were recorded at higher ethanol concentration (up to 75%), and any further increase in ethanol concentration beyond 75% will decrease the flavonoids yield. This may be due to that 75% aqueous ethanol represents the most suitable polarity for flavonoids extraction and also the presence of water increases the swelling index and contact surface area of plant material with the solvent [83,84].…”
Section: Extraction Of Flavonoidsmentioning
confidence: 98%
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“…These results could be explained by Xi and Luo [82], who found that increasing the pressure has positive effect on the solvent viscosity, diffusion and surface tension, thus increases solubility of the natural compounds, but further increase in the pressure can damage these compounds. Xi and Yan [81] had also shown that higher yield of flavonoids were recorded at higher ethanol concentration (up to 75%), and any further increase in ethanol concentration beyond 75% will decrease the flavonoids yield. This may be due to that 75% aqueous ethanol represents the most suitable polarity for flavonoids extraction and also the presence of water increases the swelling index and contact surface area of plant material with the solvent [83,84].…”
Section: Extraction Of Flavonoidsmentioning
confidence: 98%
“…Xi and Yan [81] optimized the conditions such as pressure, ethanol concentration, and solvent to solid ratio, temperature and extraction time for proper PSE extraction of flavonoids from Flos Sophorae and compared it with HRE. Yield of flavonoids was improved by increasing the pressure up to 450 MPa, after that any increase in the pressure caused a decrease in the yield of flavonoids.…”
Section: Extraction Of Flavonoidsmentioning
confidence: 99%
“…The flavonoid content was measured by a colorimetric method (ESI, Fig. S2), which is based on the formation of a flavonoid-aluminum complex with maximum absorption at 415 nm [31]. 1 mL of standard or extract was added to 1 mL of AlCl 3 .6H 2 O solution.…”
Section: Measurement Of Total Flavonoid Compoundsmentioning
confidence: 99%
“…A similar outcome was reported by using HP to obtain flavonoids from white buds of Flos Sophorae. 129 The extraction was optimized using a response surface methodology where pressure, percentage of ethanol in the solvent and the liquid/solid ratio were selected as the main variables. According to the authors, the most efficient extracting conditions were 460 MPa, 75% ethanol solution and a liquid to solid ratio of 32 mL g −1 , which yielded 203 mg flavonoids per g.…”
Section: Application Of Hp In Sustainable Extractionmentioning
confidence: 99%