This article presents the current state of affairs in cases of explosions in Ukraine and preventive measures to protect against them. The relevance of studies on the substantiation of the methodology for calculating the parameters of easily disposable structures for explosive and fire hazardous premises has been determined. The analysis of domestic and foreign regulatory documents for the design and installation of window openings in buildings for various purposes is carried out. The permissible values of the overpressure of the explosion, which does not cause significant damage to building structures and is safe for people, are considered. The subject of the study is the effect of the amount of gas on the design parameters of the research stand for the experimental evaluation of easily disposable structures. The purpose of this work is to substantiate the design and the main technical parameters of the research stand for assessing the performance of easily sisposable structures. The essence of the proposed research method is to create an excess pressure from the explosion of a mixture of propane-butane with air in the working volume and to study the effect of this excess pressure of the explosion on a prototype of an easily disposable structure. An experimental stand for studying the processes of the influence of the magnitude of the overpressure of an explosion in a confined space on the design parameters of easily disposable structures is simple in design, provides an imitation of a part of a building (structure) fragment and makes it possible to study the possibility of using certain building materials with different geometric parameters as easily disposable structures, which, in turn, allows the researcher to obtain more reliable data for analysis. The existing experimental methods for evaluating the parameters of easily disposable structures are analyzed. The dimensions of the research stand and the parameters of its enclosing structures, the critical values of the overpressure of the explosion, which the stand should create, and the minimum amount of gas, the combustion of which will provide the necessary overpressure of the explosion in the stand, are substantiated. A fundamentally new stand for the experimental evaluation of the parameters of easily disposable structures, a program and experimental research methodology have been developed.