“…Central composite design response surface methodology (CCD-RSM) is a widely used optimization tool in food research (Betiku & Adesina, 2013;Betiku & Taiwo, 2015;Chen, Chen, & Lin, 2005;Dhillon, Brar, Verma, & Tyagi, 2011;Emeko, Olugbogi, & Betiku, 2015;Fasuan, Gbadamosi, & Akanbi, 2018;Fasuan, Omobuwajo, & Gbadamosi, 2017;Naveena, Altaf, Bhadraya, Madhavenda, & Reddy, 2005). Artificial neural network (ANN) is a technique that has ability to imitate the neurological processing skill of the human brain; and has been used in modeling of some food processing studies.…”