Optimization of Synthesis of Nitroimidazoles and Nitropyrazoles Based on Polarographic Investigations

Half a Century of Research Using Polarography

“…Our polarographic studies found applications in medical sciences (199,204,(264)(265)(266)(267)(268), industrial hygiene (38,269), determination of pesticides (40-43, 153, 238, 245), and solution of some problems in organic synthesis (75,192).…”

“…Exceptions are compounds bearing large substituents in the vicinity of the electroactive center and ortho-substituted aromatic compounds, where individual, specific effects predominate. For correlations using LFERs the data were obtained mostly from the literature, but successful correlations have been obtained also for our 8 P. ZUMAN experimental data for reductions of aromatic aldehydes and ketones (67,68,72), semicarbazones (66), N-and O-substituted oximes (73), sydnones (58), and nitro compounds (74,75) as well as nitrosobenzenes (76,77), nitriles (69), sulfones (78), and sulfonamides (79).…”