Optimization of the formulation of an original hydrogel-based bone cement using a mixture design

Ly, O.; Monchau, F.; Rémond, Sébastien; Lors, Christine; Jouanneaux, A.; Debarre, E.; Damidot, D.

doi:10.1016/j.jmbbm.2020.103886

Cited by 12 publications

(8 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The summary of fit for both responses is shown in Fig. and ascertain that the transformed response values are of the same order of magnitude to improve the accuracy of pure error evaluation and lack of fit tests [35]. The transformed response functions, which are less skewed, are shown in Fig.…”

Section: Design Of Experimentsmentioning

confidence: 87%

Continuous rotary membrane emulsification for the production of sustainable Pickering emulsions

Ekanem

Wilson

Scott

et al. 2022

Chemical Engineering Science

View full text Add to dashboard Cite

Section: Design Of Experimentsmentioning

confidence: 87%

Continuous rotary membrane emulsification for the production of sustainable Pickering emulsions

Ekanem

Wilson

Scott

et al. 2022

Chemical Engineering Science

View full text Add to dashboard Cite

“…Superabsorbent polymers [303][304][305] may be useful for creating bone tissue scaffolds using the calcium silicate cements. 306 Combining calcium silicate with calcium aluminate cements may contribute to faster setting and acid resistance for use in infected sites. Acid resistant cements would find temporary or long term khalil use as a core material or cement for fixed prosthodontic devices, or as a restorative material.…”

Section: Future For Calcium Silicate and Calcium Aluminate Cementsmentioning

confidence: 99%

Calcium silicate and calcium aluminate cements for dentistry reviewed

et al. 2021

View full text Add to dashboard Cite

Calcium silicate cements were identified as excellent materials for dentistry, particularly for dental procedures contacting the dental pulp or root system. Both calcium silicate and calcium aluminate cements cause the biomineralization (precipitation of hydroxyapatite [HA] phenomena and shield dental tissues from the underlying cement (a foreign body material). The cements also elute ions to stimulate cytokines that contribute to the healing of the dental pulp or in the tissue surrounding the root of a tooth. The cements serve as a foundation for other dental restorative materials. This paper reviews the cement phases, properties, in vivo reactions, and clinical benefits from the use of calcium silicate and calcium aluminate ceramic cements.

show abstract

“…Superabsorbent hydrogels are hydrophilic, three‐dimensional networks that can easily swell with water or other liquids up to thousands of times their own dry weight while maintaining their physical dimension structures. Because of their exceptional properties, they are widely used in various industrial applications such as agriculture, foods, personal care products, cosmetics, medicines and other biomedical applications 1–3 . Hydrogels that respond to external conditions such as heat, pH, chemical environments, etc., are often referred to as smart hydrogels.…”

Section: Introductionmentioning

confidence: 99%

“…Because of their exceptional properties, they are widely used in various industrial applications such as agriculture, foods, personal care products, cosmetics, medicines and other biomedical applications. [1][2][3] Hydrogels that respond to external conditions such as heat, pH, chemical environments, etc., are often referred to as smart hydrogels. Among the smart hydrogels, pH-sensitive ones have been investigated and used widely because of their useful properties for drug delivery and other biomedical proposes.…”

Section: Introductionmentioning

confidence: 99%

Preparation and characterization of pH‐sensitive carboxymethyl cellulose‐based hydrogels for controlled drug delivery

Pourkhatoun

Kalantari

Kamyabi

2022

Polymer International

View full text Add to dashboard Cite

A novel biopolymer-based hydrogel with pH-responsive behavior was synthesized by free radical polymerization of acrylic acid and methacrylic acid onto carboxymethylcellulose. The effects of initiator concentration, crosslinker concentration, acrylic acid and methacrylic acid total volume and acrylic acid percentage on water absorbency were studied using central composite design with the response surface method (RSM). The results indicate that the maximum water absorbency in distilled water is 103 g g −1 and the optimum conditions determined using RSM are: initiator concentration, 0.006105 mol L −1 ; crosslinker concentration, 0.009035 mol L −1 ; acrylic acid and methacrylic acid total volume, 2 mL; acrylic acid percentage, 50%, in a system of 35 mL total volume. The optimized hydrogel was characterized using Fourier transform infrared spectroscopy, scanning electron microscopy and thermogravimetric analysis, and its pH-responsive behavior was also evaluated using acidic and basic solutions for its possible use in control drug delivery. In this respect, ofloxacin was used as a drug model and experimental data showed that the hydrogel is a possible candidate for injectable drug delivery.

show abstract

Optimization of the formulation of an original hydrogel-based bone cement using a mixture design

Cited by 12 publications

References 30 publications

Continuous rotary membrane emulsification for the production of sustainable Pickering emulsions

Continuous rotary membrane emulsification for the production of sustainable Pickering emulsions

Calcium silicate and calcium aluminate cements for dentistry reviewed

Preparation and characterization of pH‐sensitive carboxymethyl cellulose‐based hydrogels for controlled drug delivery

Contact Info

Product

Resources

About