Optimization of the incubation parameters for biogenic synthesis of WO3 nanoparticles using Taguchi method

Spark plasma sintering (SPS) tests were designed using the Taguchi method to create high‐performance composites consisting of 60 wt% TiB2, 30 wt% TiC, and 10 wt% Ti. The effects of SPS parameters on the microstructure and mechanical properties of TiB2‐TiC‐TiB composites were systematically investigated. Additionally, the evolution of phase and microstructure during the densification of the composites was analyzed in detail. It has been demonstrated that composites can achieve a high relative density of 99.8%, a hardness of 22.2 GPa, a strength of 739 MPa, and a fracture toughness of 7.07 MPa m1/2, as well as a dense structure and small grain size. These properties can be obtained by sintering at a temperature of 1500°C, a pressure of 50 MPa, and a holding time of 5 min. Sintering temperature is the primary factor that promotes the densification of the composite and influences its relative density, grain size, and morphology. Holding time and sintering pressure are relatively minor factors, but they play important roles at different stages of the sintering process.

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“…The density and hardness errors were 2.1% and 6.8%, respectively. Although slightly larger, the data were still considered reliable 49–54 …”

Section: Resultsmentioning

confidence: 99%

“…Although slightly larger, the data were still considered reliable. [49][50][51][52][53][54] F I G U R E 3 Curves of temperature, pressure, and displacement with sintering time of composite under the optimal sintering process.…”

Section: Influence Of Sps Process Parameters On the Density And Hardn...mentioning

confidence: 99%

The effect of spark plasma sintering parameters on the densification and mechanical properties of TiB₂‐TiC‐TiB composites

Liu

Zhang

Jia

et al. 2023

Int J Applied Ceramic Tech

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“…One advantage of the Taguchi DOE is that it minimizes or optimizes the number of experimental runs required to complete the experiment. For this investigation, the Taguchi DOE was chosen [22][23][24]. The three levels of each input factor were used in the development of the L27 orthogonal array.…”

Section: Methodsmentioning

confidence: 99%

Exploring machine vision measurements through innovative cyclic-lead-follower statistical technique: an experimental study

Zende,

Pawade

2024

Eng. Res. Express

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In metrology systems, machine vision systems are often utilized for non-contact inspection. The most important phase in ensuring measurement accuracy is camera calibration and estimation of pixel measurement errors, which establish the correspondence between image coordinates and object coordinates. Multiple calibration techniques improve the effectiveness of machine vision systems. However, a number of factors lead to variations in the camera calibration procedure, which must be optimized. This study explains a novel 'Cyclic-Lead-Follower' statistical methodology proposed for camera calibration and measurement to estimate the errors in pixel measurement, employing four slip gauges for measurement. Several multi-criteria decision-making techniques, including WSM, WPM, WASPAS, and TOPSIS, were used to optimize the results of the proposed Cyclic-Lead-Follower methods. The proposed Cyclic-Lead-Follower method improves the accuracy of the camera calibration and measurement system, which employs the exponential moving average statistical method when compared to the traditional calibration method. The proposed calibration method produces lower exponential moving average values than the traditional calibration method, with an average percentage error of approximately 46% in the exponential moving average. The use of an exponential moving average in a validation experiment of the Cyclic-Lead-Follower method decreased the measurement percentage errors, which were estimated to be 0.57%. The proposed method can be used in machine vision systems due to its robustness, accuracy, and cost-effectiveness.

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“…In recent pharmaceutical world, there has been a tremendous implementation of design of experiment with a focus on statistical application. Taguchi design is an experimental process which ensures the minimization of process error by performing robust design (Francis et al, 2022; Shafiee et al, 2022). The design identifies the variables also known as main effects which have significant impact in an experiment.…”

Section: Introductionmentioning

confidence: 99%

Formulation, optimization and characterization of raloxifene hydrochloride loaded PLGA nanoparticles by using Taguchi design for breast cancer application

Maddiboyina¹,

Roy

Nakkala³

et al. 2023

Chem Biol Drug Des

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Multidrug resistance in breast cancer and the associated side‐effects of anticancer therapies are significant hurdles in chemotherapy‐based treatment. Biodegradable polymeric nano‐based targeted drug delivery technologies showed tremendous advantages in targeted local delivery with limited off‐targeted side effects. Therefore, there is a persistent need to develop targeted nanomedicine systems for treatment of breast cancer. The current research attempted to develop poly (lactic‐co‐glycolic acid) nanoparticles loaded with raloxifene by modified emulsification solvent diffusion evaporation method to improve oral bioavailability by using Taguchi design. It was observed that the optimized formulation (1:4 drug to polymer ratio) poly (lactic‐co‐glycolic acid) showed a mean particle size and Polydispersity index of 218 ± 23.7 nm and 0.231 ± 0.04, respectively. The entrapment efficiency was found to be 82.30% ± 1.02%. In vitro drug delivery was found to be 92.5% ± 1.48% in 40 h. The nanoparticles were to remain stable at 2°C–8°C even after 30 days. Differential scanning calorimetry and Fourier transform infrared spectroscopy characterization techniques showed that there was no interaction between the drug and excipient. Stability studies indicate that polymeric nanoparticles were stable at 2°C–8°C after 6 months. Raloxifene nanoparticles may be the most potent targeting moieties to treat highly invasive and metastatic MCF‐7 breast cancer cells.

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Optimization of the incubation parameters for biogenic synthesis of WO3 nanoparticles using Taguchi method

Cited by 9 publications

References 79 publications

The effect of spark plasma sintering parameters on the densification and mechanical properties of TiB₂‐TiC‐TiB composites

The effect of spark plasma sintering parameters on the densification and mechanical properties of TiB₂‐TiC‐TiB composites

Exploring machine vision measurements through innovative cyclic-lead-follower statistical technique: an experimental study

Formulation, optimization and characterization of raloxifene hydrochloride loaded PLGA nanoparticles by using Taguchi design for breast cancer application

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Optimization of the incubation parameters for biogenic synthesis of WO3 nanoparticles using Taguchi method

Cited by 9 publications

References 79 publications

The effect of spark plasma sintering parameters on the densification and mechanical properties of TiB2‐TiC‐TiB composites

The effect of spark plasma sintering parameters on the densification and mechanical properties of TiB2‐TiC‐TiB composites

Exploring machine vision measurements through innovative cyclic-lead-follower statistical technique: an experimental study

Formulation, optimization and characterization of raloxifene hydrochloride loaded PLGA nanoparticles by using Taguchi design for breast cancer application

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Product

Resources

About

The effect of spark plasma sintering parameters on the densification and mechanical properties of TiB₂‐TiC‐TiB composites

The effect of spark plasma sintering parameters on the densification and mechanical properties of TiB₂‐TiC‐TiB composites