2021
DOI: 10.3390/toxins13110767
|View full text |Cite
|
Sign up to set email alerts
|

Optimization of the QuEChERS-Based Analytical Method for Investigation of 11 Mycotoxin Residues in Feed Ingredients and Compound Feeds

Abstract: Mycotoxins are toxic substances naturally produced by various fungi, and these compounds not only inflict economic damage, but also pose risks to human and animal health. The goal of the present study was to optimize the QuEChERS-based extraction and liquid chromatography–tandem mass spectrometry (LC–MS/MS) method for the analysis of 11 mycotoxins, such as aflatoxins (AFs), ochratoxin A (OTA), fumonisins (FBs), T-2 toxin, HT-2 toxin, zearalenone (ZEN), and deoxynivalenol (DON), commonly found in feed. The QuEC… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

0
12
0

Year Published

2022
2022
2025
2025

Publication Types

Select...
8

Relationship

0
8

Authors

Journals

citations
Cited by 16 publications
(12 citation statements)
references
References 66 publications
0
12
0
Order By: Relevance
“…Multifunction impurity adsorption (MIA) cleaning is a method based on matrix dispersion solid-phase extraction, which is mainly based on the selection of a variety of functionalized adsorbent materials to adsorb the main interfering impurities in a sample. This effectively removes phospholipids, pigments, and other substances that may be present in the matrix while leaving the measured substances in the sample solution and achieving purification and enrichment, which can save time for sample pre-treatment [ 25 ]. According to the adsorption characteristics of different materials such as BONDESIL-SI sorbent, which is based on a bonded reversed-phase (with high-purity irregular silica gel as the matrix and end-group capping treatment), a typical reversed-phase extraction retention mechanism has excellent strength retention properties for non-polar compounds and can remove lipids from samples.…”
Section: Resultsmentioning
confidence: 99%
See 2 more Smart Citations
“…Multifunction impurity adsorption (MIA) cleaning is a method based on matrix dispersion solid-phase extraction, which is mainly based on the selection of a variety of functionalized adsorbent materials to adsorb the main interfering impurities in a sample. This effectively removes phospholipids, pigments, and other substances that may be present in the matrix while leaving the measured substances in the sample solution and achieving purification and enrichment, which can save time for sample pre-treatment [ 25 ]. According to the adsorption characteristics of different materials such as BONDESIL-SI sorbent, which is based on a bonded reversed-phase (with high-purity irregular silica gel as the matrix and end-group capping treatment), a typical reversed-phase extraction retention mechanism has excellent strength retention properties for non-polar compounds and can remove lipids from samples.…”
Section: Resultsmentioning
confidence: 99%
“…Even when relying only on LC, it may have low sensitivity and is prone to false positives. LC-MS/MS, with good selectivity and specificity and a low detection limit, has become a popular direction for the study of mycotoxins in recent years, and several methods for detecting multiple mycotoxins in maize have been published [ 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 ]. The limits of quantification (LOQ) of various toxins are as follows: AFs (0.05~1.6 μg/kg), T-2 (0.05~0.3 μg/kg), DON (0.94~13.6 μg/kg), ZEN (0.5~0.72 μg/kg), OTA (0.03~0.3 μg)/kg), and FBs (1.0∼8.2 μg/kg).…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…However, the choice of extraction solvent is dependent on several factors, such as the number of analytes in the final methodology, range of polarities of the suite of analytes and their stability in the extraction solvent chosen. In many cases, the extraction of Fusarium type-A trichothecenes such as HT-2 and T-2 is performed using an admixture of an organic solvent with water, with ratios of acetonitrile: water between (50:50, v : v ) and (80:20, v : v ), with the addition of 0.3–10% formic or acidic acid [ 120 , 121 , 122 , 123 ]. Incidentally, the use of acetonitrile can be substituted for methanol in some cases.…”
Section: Methodsmentioning
confidence: 99%
“…In the last few years much of the literature has focused on multi‐mycotoxin methods especially using QuEChERS and LC–MS/MS in different feed materials (e.g. Nakhjavan et al., 2020 ; Nualkaw et al., 2020 ; Jo et al., 2021 ; Gonzales‐Jartin et al., 2021 ; Konak et al., 2021 ; Seo et al., 2021 ; Bi et al., 2022 ; Mackay et al., 2022 ; Nochetto and Li, 2022 ). However, there has also been focus on other and often faster methods including those with biosensors that often involve specific antibodies, aptamers or molecular imprinting polymers in the analytical work (e.g.…”
Section: Introductionmentioning
confidence: 99%