Optimization of the synthesis conditions of products formed in arenesulfonylation of N-alkylated anilines

Reactivity of Benzamide toward Sulfonylation

“…where χ 0 , χ τ , and χ ∞ are the conductivities of the reaction mixture at the initial moment, at a moment of time τ, and after completion of the reaction, respectively; c 0 sc is the initial concentration of 2; x is the change of the concentration of 2 by a moment of time τ. The rate constants for the hydrolysis of 2 (k h ) were determined by us previously [8].…”

“…Compounds containing an amino group have long been the subjects of our studies, as they are substrates of acylation reactions, including sulfonylation. We previously performed systematic studies of the kinetics and mechanisms of acylation of various amines such as ammonia, α-amino acids, dipeptides, benzoic and benzenesulfonic acid hydrazides, benzenesulfonamide, and 2-sulfobenzoic acid imide [4][5][6][7][8]. Among amino compounds that are promising as substrates for sulfonylation, arenecarboxylic acid amides remain almost unstudied.…”