Optimization of ultrasound-assisted extraction of glycyrrhizic acid from licorice using response surface methodology

Jang, Seol; Lee, A Yeong; Lee, A. Reum; Choi, Goya; Kim, Ho Kyoung

doi:10.1016/j.imr.2017.08.003

Cited by 50 publications

(23 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Adsorption is spontaneous and exothermic, and is expected to decrease with temperature increase. However, studies have also found the opposite or no relationship between changes in temperature and the amount of adsorbed substance [ 30 ]. Studies on the effect of temperature on 2,4-D adsorption using activated carbon have reported that surface activation and the breaking of existing bonds causes new active sites on the carbon surface, thereby increasing its adsorption efficiency.…”

Section: Resultsmentioning

confidence: 99%

Process Development for the Detoxification of Fermentation Inhibitors from Acid Pretreated Microalgae Hydrolysate

et al. 2021

View full text Add to dashboard Cite

The aim of this study was to remove 5-hydroxymethyl furfural (5-HMF) and furfural, known as fermentation inhibitors, in acid pretreated hydrolysates (APH) obtained from Scenedesmus obliquus using activated carbon. Microwave-assisted pretreatment was used to produce APH containing glucose, xylose, and fermentation inhibitors (5-HMF, furfural). The response surface methodology was applied to optimize key detoxification variables such as temperature (16.5–58.5 °C), time (0.5–5.5 h), and solid–liquid (S-L) ratio of activated carbon (0.6–7.4 w/v%). Three variables showed significant effects on the removal of fermentation inhibitors. The optimum detoxification conditions with the maximum removal of fermentation inhibitors and the minimum loss of sugars (glucose and xylose) were as follows: temperature of 36.6 °C, extraction time of 3.86 h, and S-L ratio of 3.3 w/v%. Under these conditions, removal of 5-HMF, furfural, and sugars were 71.6, 83.1, and 2.44%, respectively, which agreed closely with the predicted values. When the APH and detoxified APH were used for ethanol fermentation by S. cerevisiae, the ethanol produced was 38.5% and 84.5% of the theoretical yields, respectively, which confirmed that detoxification using activated carbon was effective in removing fermentation inhibitors and increasing fermentation yield without significant removal of fermentable sugars.

show abstract

Section: Resultsmentioning

confidence: 99%

Process Development for the Detoxification of Fermentation Inhibitors from Acid Pretreated Microalgae Hydrolysate

et al. 2021

View full text Add to dashboard Cite

show abstract

“…This technique has great extraction efficiency due to the acoustic cavitation effects that occur in the solvent by ultrasonic waves, and this depends on ultrasonic properties, product characteristics, and ambient conditions. With increasing ultrasonic power, the cavitation effect increases the release of the analyte from the sample by providing better penetration of the solvent into the sample (Jang et al, 2017). On the other hand, ultrasonic power boosts can also hinder the release of bioactives from the cells, thus preventing an increase in yield during extended extraction (Vilkhu et al, 2008;Guo et al, 2019).…”

Section: Ultrasound Extraction Using An Ultrasonic Processormentioning

confidence: 99%

Comparison of extraction methods optimised by RSM for extraction of some bioactives from liquorice samples

ÖZCAN¹,

Özcan²,

Us³

et al. 2020

Turk J Agric For

View full text Add to dashboard Cite

This study compared the extraction efficiency of 3 different techniques, ultrasound-assisted extraction (UAE), microwaveassisted extraction (MAE), and the classical extraction method, in obtaining some bioactive and allergen compounds, namely liquiritin (LQ), glycyrrhizin (GL), glycyrrhetinic acid (GA), and carbenoxolone (CBX), from liquorice samples of Glycyrrhiza glabra grown in Turkey. Extraction parameters for each technique were optimised by the response surface methodology-central composite design approach. Concentrations of LQ, GL, GA, and CBX, which were selected as the responses of selected independent variables, were determined by liquid chromatography-electrospray ionisation tandem mass spectrometry. One-way variance analysis was performed to evaluate the significance of the results. MAE was revealed as the most effective technique for extracting LQ (mean: 8.52 mg g −1 ), GL (mean: 76.65 mg g −1 ), and GA (mean: 1138.84 µg g −1 ) from liquorice, while the classical technique was the most effective for obtaining CBX (mean: 5.75 µg g −1 ).

show abstract

“…ANOVA output for Y1 and Y2 is provided in Tables 3 and 4, respectively. ANOVA gives us the information about the level of significance in terms of p-value which should be less than 0.05 for a term to be significant [23]. It is observed that all the linear terms viz.…”

Section: Development Of Regression Model and Statistical Analysismentioning

confidence: 99%

Optimization of electrocoagulation process for fluoride removal: a blending approach using gypsum plaster rich wastewater

Jadhao

Kodape

Junghare

2019

Sustain Environ Res

View full text Add to dashboard Cite

A novel blending approach has been introduced for fluoride removal by means of electrocoagulation. A blend was prepared by mixing synthetic phosphoric acid plant wastewater and gypsum plaster (GP) rich wastewater. This study explores defluoridation of wastewater using the simultaneous effect of chemical precipitation and electrocoagulation. Fourier transform infrared spectroscopy analysis of sludge confirms the presence Ca-F bond, which proves that enhancement in fluoride removal with blending of GP rich wastewater is due to simultaneous action of chemical precipitation and electrocoagulation. Optimization and statistical modeling were done with the help of MINITAB 17 software. Response surface methodology was performed using Box-Behnken Design to predict the fluoride removal efficiency and energy consumption. R 2 values of 0.9485 and 0.9998 shows a good agreement between experimental and predicted values of responses. Kinetic study was done to determine the rate constant and it is found out that fluoride removal follows second order kinetic model. Blending approach confirmed the assistive role of GP rich wastewater in the enhancement of fluoride removal efficiency.

show abstract

Optimization of ultrasound-assisted extraction of glycyrrhizic acid from licorice using response surface methodology

Cited by 50 publications

References 35 publications

Process Development for the Detoxification of Fermentation Inhibitors from Acid Pretreated Microalgae Hydrolysate

Process Development for the Detoxification of Fermentation Inhibitors from Acid Pretreated Microalgae Hydrolysate

Comparison of extraction methods optimised by RSM for extraction of some bioactives from liquorice samples

Optimization of electrocoagulation process for fluoride removal: a blending approach using gypsum plaster rich wastewater

Contact Info

Product

Resources

About