This paper describes the design, characterization, and testing of a compact hydrophone capable of measuring acoustic signals from cardiomyocytes. Our hydrophone consists of a nanofabricated photonic-crystal diaphragm externally-mounted to the facet of an optical fiber to form a pressure-sensitive Fabry-Pérot cavity. Our hydrophone can operate in small liquid volumes less than 5 mm deep and incorporates a microchannel to vent air during immersion. The venting channel is designed to optimize bandwidth and sensitivity. Modeling and experimental results in water show a bandwidth from 50 Hz to 18 kHz and a minimum detectable pressure of 3 µP a/
√Hz. We demonstrate the sensitivity to simulated bio-acoustic sources with nanometer-scale displacements.