Optimized ultrasound imaging catheters for use in the vascular system

Crowley, Robert J.; Behren, Patrick L. Von; Couvillon, L. A.; E., D.; Abele, John E.

doi:10.1007/978-94-009-1007-2_8

Cited by 7 publications

(9 citation statements)

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“…The, ultrasound area was on average 10-7 mm2 greater than that measured histologically (CI for an individual ultrasound area 3-2-18-2 mm2 > histological area, CI for the mean difference 9-8-11-6 mm2). By contrast (fig 6) there was close agreement between the histological and photographic techniques (mean difference -1-3 mm2, CI ofan individual histological area measurement -4-3 to + 1 6 mm2 compared with the photographic 20 Average lumen area by IVUS and direct measurement (mm2) -5 Figure 7 Difference between luminal area measured by the intravascular ultrasound system and the measured diameter ofpolyethylene tubes plotted against the mean of the two values. Fixed lines show the mean of the difference and 2 SD from this mean.…”

Section: Experimental Protocolmentioning

confidence: 80%

Intravascular ultrasound imaging of the coronary arteries: an in vitro evaluation of measurement of area of the lumen and atheroma characterisation

Anderson¹,

Simpson²,

Katritsis³

et al. 1992

Heart

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Objective-To assess the accuracy of measurement of area of the lumen, and sensitivity, and specificity of detection of atheroma in coronary arteries in vitro with a commercially available 20 MHz intravascular ultrasound system.Setting-A teaching hospital department of cardiology with the support of the department of cardiovascular pathology.Procedure-10 segments of coronary artery were removed from cadaver hearts. Intravascular ultrasound imaging was performed at fixed levels and the vessels were then sectioned and photographed before histological preparation. An independent blinded observer measured luminal area and assessed the presence of atheroma on the intravascular ultrasound images of 76 vessel sections (304 quadrants). The sensitivity and specificity of detection of atheroma was assessed in comparison with the histologically prepared sections. Luminal areas from intravascular ultrasound, photographs of cross sections of the vessels and histological sections were compared with the technique of limits of agreement.Results-Overall 36% of the 304 quadrants studied histologically had identifiable atheroma. Intravascular ultrasound sensitivity for atheroma was 0 593 and the specificity was 0-839. The positive predictive value was 0-674, and the relative risk 3X139. Values for area of the vessel lumen were on average 9-4 mm2 (confidence interval (CI) 8-6-10-2 mm2) larger than those measured from photographs and 10-7 (CI 9-8-11-6 mm2) larger than those measured from the histological sections.Conclusions-The intravascular ultrasound system assessed in this study significantly overestimated coronary vessel luminal area and had low sensitivity and specificity for detection of atheroma. Improvements in image resolution are required before this system can provide useful information on coronary artery size and morphology. (Br Heart J 1992;48:276-8 1)The concept of imaging the coronary arteries from within the lumen with ultrasound is not new but early attempts were limited by catheter technology.' The development over the last 15 years of intravascular interventional procedures such as angioplasty and atherectomy has renewed interest in intravascular imaging. The realisation that the distribution and structure of the atheromatous plaque are important factors affecting the success of these strategies spurred interest in intravascular ultrasound and angioscopy. Imaging of the vessel after the intervention would enable assessment of the response of the atheroma to the treatment and identification of features associated with satisfactory long-term outcome. Although angioscopy can achieve imaging in front of the catheter tip it provides information on surface appearance only whereas intravascular ultrasound has the potential advantage of providing information on the deeper composition of the vessel wall including atheromatous plaques. This tantalising prospect is responsible for the current explosion of interest in intravascular ultrasound techniques.Recently published studies have shown excellent correlation of v...

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Section: Experimental Protocolmentioning

confidence: 80%

Intravascular ultrasound imaging of the coronary arteries: an in vitro evaluation of measurement of area of the lumen and atheroma characterisation

Anderson¹,

Simpson²,

Katritsis³

et al. 1992

Heart

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“…Our own initial work in laser angioplasty had been to develop a system of catheters that would prevent perforation of arteries by incorporating US guidance [4,10,11]. We had speculated that hybrid catheters with both ablating and imaging capabilities would have commercial importance, and were encouraged by feasibility experiments that showed us that certain vessel features and disease could be resolved with high frequency imaging technology [121.…”

Section: Laser Hybridsmentioning

confidence: 99%

“…A variety of transducer frequencies, catheter sizes and configurations, a few with unique capabilities, offer more optimal imaging of different intraluminal conditions and calibers [4]. At least two potentially competing imaging methods, single crystal (mechanically scanned) and synthetic aperture (electronically scanned) are available.…”

Section: Introductionmentioning

confidence: 99%

Ultrasound guided therapeutic catheters: recent developments and clinical results

et al. 1991

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The increasing use of intravascular ultrasound technology by clinicians is providing detailed and immediate information about the results of interventions, and this is stimulating the development of new catheters that use ultrasound imaging to control therapy in real time. Cold and thermal balloon angioplasty, atherectomy, embolectomy, laser ablation and rotational recanalization are a few of the interesting capabilities now being added to ultrasound catheters. We report on the development and characteristics of some of these devices and attempt to assess their potential to precisely direct therapy.

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“…Smaller transducers provide less tissue penetration of the ultrasound beam because of emission of lower energy. 9 Although the lateral resolution in the near field is better with smaller IVUS transducers, the focal zone is shorter compared with larger catheters. 9,10 Despite these limitations, the 0.018-inch imaging core provided similar image quality compared with the 0.029-inch imaging core in terms of plaque boundary recognition and tissue characteristics.…”

Section: 018-inch 32f Imaging Core Imaging Devicementioning

confidence: 99%