2024
DOI: 10.3389/fimmu.2024.1462697
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Optimizing cancer treatment: the synergistic potential of CAR-T cell therapy and CRISPR/Cas9

Maryam Amiri,
Amir Kian Moaveni,
Masoumeh Majidi Zolbin
et al.

Abstract: Optimizing cancer treatment has become a pivotal goal in modern oncology, with advancements in immunotherapy and genetic engineering offering promising avenues. CAR-T cell therapy, a revolutionary approach that harnesses the body’s own immune cells to target and destroy cancer cells, has shown remarkable success, particularly in treating acute lymphoblastic leukemia (ALL), and in treating other hematologic malignancies. While CAR-T cell therapy has shown promise, challenges such as high cost and manufacturing … Show more

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