Optimizing sequential gene expression modulation for cellular reprogramming - Coupled Boolean modeling and Reinforcement Learning based method
Vivek Singh
Abstract:Regenerative medicine entails regenerating damaged cells and tissues from healthy cells through the process of cellular reprogramming. The most common method to achieve reprogramming of cells of one type to another is by modulating the activity of specific genes. However, identifying the most suitable genes for reprogramming is a challenge due to their large number in humans and their complex interactions. This study describes a computational method to predict sequential gene expression modulation for reprogra… Show more
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