“…Based on the nonclassical biomineralization theory, the biomineralized scaffold could be synthesized with unique intra-and extrafibrillar mineralization structures close to the nanoscale morphology of natural bone. 3 During the polymer-induced liquid precursor (PILP) process, personalized functional optimization can be achieved by modifying the collagen template and PILP system, 4,5 showing promising transformation value in bone tissue regeneration. 6 The immune response and foreign body reactions elicited by calcium phosphate materials have been noticed in the early years.…”