Optimizing the Extraction and Encapsulation of Mucilage from Brasenia Schreberi

Abstract

The mucilage from Brasenia schreberi (BS) exhibits various biological activities, including antialgal, antibacterial, soluble-fiber properties, and excellent lubricating behavior. Thus, the extraction and wide use of mucilage in the food industry are crucial. In this study, the high-speed shear-assisted extraction of mucilage from BS was optimized by using response surface methodology (RSM). The optimal extraction conditions were as follows: Extraction temperature of 82 °C, extraction time of 113 min, liquid–solid ratio of 47 mL/g, and shear speed of 10,000 rpm. Under these conditions, the actual yield of BS mucilage was 71.67%, which highly matched the yield (73.44%) predicted by the regression model. Then, the BS mucilage extract was powdered to prepare the capsule, and the excipients of the capsule were screened using a single-factor test to improve the disintegration property and flowability. The final capsule formulation, which consisted of: 39% BS mucilage powder (60 meshes); 50% microcrystalline cellulose (60 meshes) as the filler; both 10% sodium starch glycolate and PVPP XL-10 (3:1, 60 meshes) as the disintegrant; both 1% colloidal silicon dioxide and sodium stearyl fumarate (1:1, 100 meshes) as the glidant by weight; were used for preparing the weights of a 320 mg/grain of capsule with 154.7 ± 0.95 mg/g polysaccharide content. Overall, the optimized extraction process had a high extraction rate for BS mucilage and the capsule formulation was designed reasonably.

Extraction and Physicochemical Characterization of Dried Powder Mucilage from Opuntia ficus-indica Cladodes and Aloe Vera Leaves: A Comparative Study

“…The medulla was cut into small pieces and placed in a 1000 mL beaker. Distilled water at room temperature was added to the beaker in a 1:2 v/v (medulla:water) ratio, and the mixture was left for 24 h. According to the literature [ 1 , 39 , 40 , 41 ], these extraction parameters ensure maximum viscosity and high yield of the extracted mucilage. The hydrated medulla pieces were manually squeezed through a nylon cloth.…”

A novel source of food hydrocolloids from Trigonella elliptica seeds: extraction of mucilage and comprehensive characterization

“…Other researchers reported similar results about the effect of water:seed ratio on mucilage extraction yield 14,16,17 . Sepúlveda et al 18 . demonstrated that when the amount of water applied for the extraction of mucilage from Opuntia ficus‐indica was increased, the efficiency exhibited a small tendency to increase.…”

“…At high seed weight, the availability of water was restricted, so by elevating extraction temperature the extraction yield increased slightly but at low seed weight it increased more intensely. Other researchers reported similar results about the effect of water:seed ratio on mucilage extraction 14,16,17 Sepúlveda et al 18 demonstrated that when the amount of water applied for the extraction of mucilage from Opuntia ficus-indica was increased, the efficiency exhibited a small tendency to increase. A similar tendency was observed at a constant temperature of 60 °C.…”