Optimizing the Tyrosinase Inhibitory and Antioxidant Activity of Mango Seed Kernels with a Response Surface Methodology

Rawdkuen, Saroat; Sai‐Ut, Samart; Benjakul, Soottawat

doi:10.1007/s12161-016-0494-6

Cited by 11 publications

(23 citation statements)

References 37 publications

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“…Thus, it is important for optimizing DH and its involved parameters, such as enzyme concentration, substrate concentration, reaction temperature, hydrolysis time, and pH, to achieve an economical and nutritional protein hydrolysate. Response surface methodology (RSM) is an effective technique applied to optimize food processing operations, which can employ several variables simultaneously and describe the overall process [ 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

Bioconversion of duck blood cell: process optimization of hydrolytic conditions and peptide hydrolysate characterization

et al. 2018

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BackgroundAs the protein-laden by-product, red blood cells (RBCs) from poultry blood is a potential source of protein used as food and feed ingredient. However, RBC was currently underutilized. Therefore, it is an urgent need to develop feasible and cost-effective methods for converting poultry waste into nutritional and functional products.ResultsTo take full advantage of this poultry waste, peptide hydrolysate was produced by deep controllable bioconversion of RBC, by means of synergistic combination of neutrase and flavourzyme. In this work, the functional properties and antioxidant activity of peptide hydrolysate were also characterized. The degree of hydrolysis (DH) was optimized using response surface methodology, and optimal hydrolysis conditions were found to be: temperature 51 °C, substrate concentration 14% (w/v), initial pH 7.0, and time 7.5 h. The red blood cell hydrolysate (RBCH) obtained not only possessed plentiful small peptides (< 3 kDa, 68.14%), but also was abundant in essential amino acids, accounting for over 50% of total amino acids. In addition to its excellent solubility (> 80%), emulsifying and foaming properties, RBCH also exhibited notable antioxidant activities, such as DPPH (2,2-diphenyl− 1-picrylhydrazyl) radical-scavenging activity (IC50, 4.16 mg/mL), reducing power, metal chelating ability and inhibiting lipid peroxidation.ConclusionsRBCH enriched in small peptides has the potential to be a new food additive with outstanding functional and antioxidant properties, and a process was established for converting poultry waste into peptide hydrolysate using neutrase and flavourzyme.Electronic supplementary materialThe online version of this article (10.1186/s12896-018-0475-5) contains supplementary material, which is available to authorized users.

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Section: Introductionmentioning

confidence: 99%

Bioconversion of duck blood cell: process optimization of hydrolytic conditions and peptide hydrolysate characterization

et al. 2018

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“…Chaiwut et al [47] have reported that they obtained a substantial extraction of proteases from papaya peels. Tyrosinase inhibitor enzyme was extracted from mango seed kernel [46,48]. Figure 10.…”

Section: Enzyme Extraction and Applicationmentioning

confidence: 99%

“…Recent studies have shown that fruit's waste parts like mango seed contain a noteworthy amount of bioactive component of therapeutic worth [48,49]. These biologically active components include mangiferin, flavonoids, catechin, phenolic acids, gallic acid, and gallic acid derivatives as shown in Figure 12.…”

Section: Fruit Seed and Kernelmentioning

confidence: 99%

“…Nam-Dokmai peel (NDP) showed significantly higher phenolic content and tyrosinase inhibitor activity than that of the Tong-Dam peel (TDP). The optimal condition that maximized the extraction yields, EPC, and the antioxidant activities for NDP were ethanol proportion of 49%, a temperature of 61°C, and an extraction time of 221 min, whereas the optimized condition that maximized the extraction yields, TPC, and antioxidant activities from mango Tong-Dam kernel (TDK) was an ethanol concentration of 62%, a temperature of 63°C, and a duration of 150 min with a fixed ratio of 1:30 solid-liquid [48].…”

Section: Bioactive Compound Extractionmentioning

confidence: 99%

“…Response surface methodology to optimize the extraction of polyphenol compounds from plant wastes. Sources: Rawdkuen et al [48] Sai-Ut et al [46]. showed good sources for bioactive compounds with high antioxidant activities.…”

Section: Legume/grain/defatted Seed Flour/rice Branmentioning

confidence: 99%

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Extraction, Characterization, and Application of Agricultural and Food Processing By-Products

Rawdkuen¹,

Ketnawa²

2020

Food Preservation and Waste Exploitation

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By-products originating from agricultural and food processing are considerable disposal problem for the industry because these waste streams emerge in huge quantities and often have direct impact on the economy and environmental pollution. However, at the same time, it constitute a rich but yet underutilized source of valuable components, which may find application as ingredients in the food and non-food industries. As a result, numerous projects are currently directed toward the utilization of agricultural and food processing by-products such as animal-based (skin, bone, flesh, and internal organs) and plant-based biomaterials (fruit peels and seeds, rice bran, and etc.). In the present work, we would like to focus on the potentialities and the current research of the compounds and extracts deriving from agro-industrial disposable wastes in the food-related utilization. The potential of selected by-products as a source of bioactive/functional compounds in terms of emerging and conventional techniques for extraction, characterization, biological activity monitoring and application of the extracts or isolated compounds as functional food ingredients or bio-based materials for food packaging are highlighted. Considering environmental effect and economic loss, agricultural and food processing by-products should be utilized in various innovative processes in the cause of beneficial product derivation.

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Phenolic compounds in mango fruit: a review

et al. 2021

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Mangifera indica fruit (mango) is one of the most commercialized fruits around the world, due to the great variety of existing cultivars from which different food products such as drinks, juices, concentrates, and jams are prepared. The wastes generated during the processing of this fruit (20 million tons), which represent up to 60% of the weight of the fruit and consist mainly of peels (12%) and kernels seeds (20%), cause a series of environmental and economic problems for entrepreneurs in the sector. This is because there are no clear policies for its disposal and reuse. Nevertheless, the development of biotechnological tools has led to these wastes becoming subject of interest for their use in multiple industries such as food and pharmaceuticals, since it has been shown that they can be used as raw material to obtain phenolic compounds with biological activities (antioxidant, antimicrobial, anticancer, etc.). This review compiles the most relevant works from 2016 to 2021 about extraction, quantification, identification, biological activities, and applications of phenolic compounds obtained from the mango tree, with special focus on the fruit, with the objective to promote the use of mango from a sustainable perspective, and with a biorefinery approach.

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Optimizing the Tyrosinase Inhibitory and Antioxidant Activity of Mango Seed Kernels with a Response Surface Methodology

Cited by 11 publications

References 37 publications

Bioconversion of duck blood cell: process optimization of hydrolytic conditions and peptide hydrolysate characterization

Bioconversion of duck blood cell: process optimization of hydrolytic conditions and peptide hydrolysate characterization

Extraction, Characterization, and Application of Agricultural and Food Processing By-Products

Phenolic compounds in mango fruit: a review

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