Optimizing waist circumference cut-points for the metabolic syndrome in a South African cohort at 3-year follow-up: the SABPA prospective cohort

Hoebel, Svelka; Malan, Leoné; Botha, Judith; Swanepoel, Mariette

doi:10.1007/s12020-014-0237-7

Cited by 14 publications

(17 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“… 15 In a prospective study in South Africa, the WC cut-off points for predicting the MetS in a cohort 152 urban Black African teachers aged between 25 and 65 years were 92 cm in men and 94 cm in women. 38 As noted by the authors, however, this study was limited by the small size and the homogeneity of the sample. In a recent study involving 1,099 subjects from Cape Town (South Africa), WC cut-off points were 84 cm in men and 94 cm in women.…”

Section: Discussionmentioning

confidence: 91%

See 1 more Smart Citation

Specific cut-off points for waist circumference and waist-to-height ratio as predictors of cardiometabolic risk in Black subjects: a cross-sectional study in Benin and Haiti

Mabchour

Delisle

Vilgrain³

et al. 2015

DMSO

View full text Add to dashboard Cite

PurposeWaist circumference (WC) and waist-to-height ratio (WHtR) are widely used as indicators of abdominal adiposity and the cut-off values have been validated primarily in Caucasians. In this study we identified the WC and WHtR cut-off points that best predicted cardiometabolic risk (CMR) in groups of African (Benin) and African ancestry (Haiti) Black subjects.MethodsThis cross-sectional study included 452 apparently healthy subjects from Cotonou (Benin) and Port-au-Prince (Haiti), 217 women and 235 men from 25 to 60 years. CMR biomarkers were the metabolic syndrome components. Additional CMR biomarkers were a high atherogenicity index (total serum cholesterol/high density lipoprotein cholesterol ≥4 in women and ≥5 in men); insulin resistance set at the 75th percentile of the calculated Homeostasis Model Assessment index (HOMA-IR); and inflammation defined as high-sensitivity C-reactive protein (hsCRP) concentrations between 3 and 10 mg/L. WC and WHtR were tested as predictors of two out of the three most prevalent CMR biomarkers. Receiver operating characteristic (ROC) curves, Youden’s index, and likelihood ratios were used to assess the performance of specific WC and WHtR cut-offs.ResultsHigh atherogenicity index (59.5%), high blood pressure (23.2%), and insulin resistance (25% by definition) were the most prevalent CMR biomarkers in the study groups. WC and WHtR were equally valid as predictors of CMR. Optimal WC cut-offs were 80 cm and 94 cm in men and women, respectively, which is exactly the reverse of the generic cut-offs. The standard 0.50 cut-off of WHtR appeared valid for men, but it had to be increased to 0.59 in women.ConclusionCMR was widespread in these population groups. The present study suggests that in order to identify Africans with high CMR, WC thresholds will have to be increased in women and lowered in men. Data on larger samples are needed.

show abstract

Section: Discussionmentioning

confidence: 91%

“…This is why we chose to determine optimal cut-off points for WC and WHtR against these most highly prevalent CMR biomarkers rather than against standard MetS components, in contrast to previous studies among Africans. 13 , 15 , 38 …”

Section: Discussionmentioning

confidence: 99%

Specific cut-off points for waist circumference and waist-to-height ratio as predictors of cardiometabolic risk in Black subjects: a cross-sectional study in Benin and Haiti

Mabchour

Delisle

Vilgrain³

et al. 2015

DMSO

View full text Add to dashboard Cite

show abstract

“…Besides, a unit site for measurement was reported among the studies. NC is measured above the cricoid cartilage and perpendicular to the long axis of the neck [ 34 , 35 ]. Due to no variation in the measurement of NC, multiple measurements are not needed to be sure about its accuracy.…”

Section: Discussionmentioning

confidence: 99%

Neck circumference and its association with cardiometabolic risk factors: a systematic review and meta-analysis

Ataie‐Jafari

Namazi

Djalalinia

et al. 2018

Diabetol Metab Syndr

View full text Add to dashboard Cite

BackgroundRecently, neck circumference (NC) has been used to predict the risk of cardiometabolic factors. This study aimed to perform a systematic review and meta-analysis to examine: (i) the sensitivity (SE) and specificity (SP) of NC to predict cardiometabolic risk factors and (ii) the association between NC and the risk of cardiometabolic parameters.MethodsA systematic search was conducted through PubMed/Medline, Institute of Scientific Information, and Scopus, until 2017 based on the search terms of metabolic syndrome (MetS) and cardio metabolic risk factors. Random-effect model was used to perform a meta-analysis and estimate the pooled SE, SP and correlation coefficient (CC).ResultsA total of 41 full texts were selected for systematic review. The pooled SE of greater NC to predict MetS was 65% (95% CI 58, 72) and 77% (95% CI 55, 99) in adult and children, respectively. Additionally, the pooled SP was 66% (95% CI 60, 72) and 66% (95% CI 48, 84) in adult and children, respectively. According to the results of meta-analysis in adults, NC had a positive and significant correlation with fasting blood sugar (FBS) (CC: 0.16, 95% CI 0.13, 0.20), HOMA-IR (0.38, 95% CI 0.25, 0.50), total cholesterol (TC) (0.07 95% CI 0.02, 0.12), triglyceride (TG) concentrations (0.23, 95% CI 0.19, 0.28) and low density lipoprotein cholesterol (LDL-C) (0.14, 95% CI 0.07, 0.22). Among children, NC was positively associated with FBS (CC: 0.12, 95% CI 0.07, 0.16), TG (CC: 0.21, 95% CI 0.17, 0.25), and TC concentrations (CC: 0.07, 95% CI 0.02, 0.12). However, it was not significant for LDL-C.ConclusionNC has a good predictive value to identify some cardiometabolic risk factors. There was a positive association between high NC and most cardiometabolic risk factors. However due to high heterogeneity, findings should be declared with caution.Electronic supplementary materialThe online version of this article (10.1186/s13098-018-0373-y) contains supplementary material, which is available to authorized users.

show abstract

“…Si on utilise les seuils génériques de TT pour définir l’OA (= 80cm chez les femmes et = 94 cm chez les hommes) [ 16 ] plutôt que les seuils spécifiques, le risque d’athérogénicité à PAP [RC (95% IC) = 8,(33-20,2); p < 0001] et d’hypertension à Cotonou [RC (95% IC) = 11,0 (36-33,9); p < 0,001] augmente (données non présentées). Dans d’autres études chez des populations noires, les seuils génériques de TT paraissaient également peu adéquats pour prédire le RCM et ce, particulièrement chez les femmes [ 9 , 10 , 48 ]. Ceci suggère de mesurer le TT en utilisant des valeurs-seuils spécifiques afin de mieux prédire le RCM chez les populations noires.…”

Section: Discussionunclassified

Obésité abdominale et autres biomarqueurs de risque cardiométabolique: influence du niveau socioéconomique et du mode de vie dans deux populations noires apparentées, Cotonou (Bénin) et Port-au-Prince (Haïti)

Mabchour

Delisle

Vilgrain³

et al. 2016

Pan Afr Med J

View full text Add to dashboard Cite

IntroductionL’augmentation du risque cardio-métabolique (RCM) dans les pays à faible et à moyen revenu résulte pour large part d’une transition nutritionnelle rapide. Cette étude est réalisée dans deux groupes de population apparentés mais vivant dans des environnements différents. Elle vise à cerner la relation entre le mode de vie et les biomarqueurs de RCM, ainsi qu’entre l’obésité abdominale (OA) et les autres biomarqueurs.MéthodesL’étude porte sur 200 Béninois de Cotonou et 252 Haïtiens de Port-au-Prince (PAP) âgés de 25 à 60 ans et apparemment en bonne santé. L’OA est définie spécifiquement par un tour de taille (TT) ≥ 88cm (hommes) et ≥ 95cm (femmes). Les autres biomarqueurs les plus fréquents sont considérés: un ratio cholestérol total/HDL-cholestérol élevé, une tension artérielle élevée et la résistance à l’insuline d’après HOMA (Homeostasis Model Assessement). Le niveau socio-économique (NSE), l’alimentation, la consommation d’alcool et de tabac sont documentés par questionnaire. Deux schémas alimentaires ressortent de l’analyse typologique, l’un traditionnel et l’autre « transitionnel », avec une fréquence accrue d’aliments occidentaux.RésultatsLe NSE, la consommation d’alcool et le tabagisme sont associés au RCM, mais non le schéma alimentaire. L’OA est associée aux autres biomarqueurs de RCM, sans effet marqué du NSE et des variables du mode de vie.ConclusionLes valeurs-seuilsspécifiques de TT se confirment. Aussi, le NSE et le mode de vie influencent le RCM mais non la relation entre l’OA et les autres biomarqueurs de RCM.

show abstract

Optimizing waist circumference cut-points for the metabolic syndrome in a South African cohort at 3-year follow-up: the SABPA prospective cohort

Cited by 14 publications

References 10 publications

Specific cut-off points for waist circumference and waist-to-height ratio as predictors of cardiometabolic risk in Black subjects: a cross-sectional study in Benin and Haiti

Specific cut-off points for waist circumference and waist-to-height ratio as predictors of cardiometabolic risk in Black subjects: a cross-sectional study in Benin and Haiti

Neck circumference and its association with cardiometabolic risk factors: a systematic review and meta-analysis

Obésité abdominale et autres biomarqueurs de risque cardiométabolique: influence du niveau socioéconomique et du mode de vie dans deux populations noires apparentées, Cotonou (Bénin) et Port-au-Prince (Haïti)

Contact Info

Product

Resources

About