Optimum treatment for primary intracranial Ewing sarcoma

Abstract

Ewing sarcoma (ES) is an aggressive, high-grade neuroectodermal neoplasm that frequently manifests in children and young adults. Although ES without osseous involvement most commonly involves paravertebral regions of the spine, it very rarely presents as a primary intracranial tumor. This report discusses a unique presentation of an adult extraosseous ES arising from the pineal region with extension into the third and fourth ventricles and multiple drop metastases to the spine. This case demonstrates the application of current chemotherapeutic and adjuvant management and offers insight into possible treatment modalities for metastasis in an atypical extraosseous ES involving the brain and spine.

Sarcoma de Ewing mesencefálico: reporte de caso

“…Existen también presentaciones extraóseas infrecuentes, que suelen afectar regiones paravertebrales de la columna; en muy raras ocasiones se presenta como un tumor primario intracraneal. 1 Se reporta el caso de una paciente de 14 años con una lesión ocupante en sistema nervioso central, en el que se arriba al diagnóstico de SE mesencefálico.…”