Options available for the infusion of lipid emulsion in home parenteral nutrition (HPN): a questionnaire survey for hospitals in Japan where HPN is practiced

Shirotani, Noriyasu; Numata, Kumiko

doi:10.1016/j.nut.2005.07.018

Cited by 4 publications

(8 citation statements)

References 22 publications

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“…For lipid‐containing emulsions, 1.2‐µm filters should be used . However, the routine use of in‐line filters is not widespread in Europe, Japan, or Australia . In several countries, guidelines recommend the use of in‐line filters in at‐risk groups such as neonates, children, immunocompromised patients, and patients who require intensive PN therapy, but not in all patients .…”

Section: Practical Handling Aspectsmentioning

confidence: 99%

Summary of Proceedings and Expert Consensus Statements From the International Summit “Lipids in Parenteral Nutrition”

Martindale

Berlana

Boullata

et al. 2020

J Parenter Enteral Nutr

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Background The 2018 Lipids in Parenteral Nutrition summit involved a panel of experts in clinical nutrition, lipid metabolism, and pharmacology, to assess the current state of knowledge and develop expert consensus statements regarding the use of intravenous lipid emulsions in various patient populations and clinical settings. The main purpose of the consensus statements is to assist healthcare professionals by providing practical guidance on common clinical questions related to the provision of lipid emulsions as part of parenteral nutrition (PN). Methods The summit was designed to allow interactive discussion and consensus development. The resulting consensus statements represent the collective opinion of the members of the expert panel, which was informed and supported by scientific evidence and clinical experience. Results The current article summarizes the key discussion topics from the summit and provides a set of consensus statements designed to complement existing evidence‐based guidelines. Lipid emulsions are a major component of PN, serving as a condensed source of energy and essential fatty acids. In addition, lipids modulate a variety of biologic functions, including inflammatory and immune responses, coagulation, and cell signaling. A growing body of evidence suggests that lipid emulsions containing ω‐3 fatty acids from fish oil confer important clinical benefits via suppression of inflammatory mediators and activation of pathways involved in the resolution of inflammation. Conclusions This article provides a set of expert consensus statements to complement formal PN guideline recommendations.

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Section: Practical Handling Aspectsmentioning

confidence: 99%

Summary of Proceedings and Expert Consensus Statements From the International Summit “Lipids in Parenteral Nutrition”

Martindale

Berlana

Boullata

et al. 2020

J Parenter Enteral Nutr

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show abstract

“…When administered separately, ILE is commonly infused through a 1.2‐µm filter (85% adult, 90% pediatric, and 81% neonatal); however, the remaining patients had ILE infused without filtration, which for some was merely a cost‐avoidance method . According to surveys performed in Europe and Japan, the use of filters is not widespread in these geographical locations …”

Section: Ile Administrationmentioning

confidence: 99%

“…As mentioned previously, the use of in‐line filters is not widespread outside of the United States . In Europe, the routine use of in‐line filters remains controversial .…”

Section: Ile Administrationmentioning

confidence: 99%

“…13 According to surveys performed in Europe and Japan, the use of filters is not widespread in these geographical locations. 31,[52][53][54] Given the significant risks of infusing particulates, including large lipid globules, there are long-standing recommendations for filtering PN admixtures in the United Kingdom and United States. 31,55 The concerns over lack of in-line filtration of PN or separately infused ILE include risks for morbidity and mortality.…”

Section: Ile Administrationmentioning

confidence: 99%

“…31 As mentioned previously, the use of in-line filters is not widespread outside of the United States. 31,[52][53][54]62 In Europe, the routine use of in-line filters remains controversial. 63 For instance, in-line filters did not significantly influence the incidence of bloodstream infections, phlebitis, morbidity, and mortality.…”

Section: Ile Administrationmentioning

confidence: 99%

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Use of Intravenous Lipid Emulsions With Parenteral Nutrition: Practical Handling Aspects

Boullata

Berlana

Piętka³

et al. 2020

J Parenter Enteral Nutr

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A number of topics important to the handling of intravenous lipid emulsions (ILEs) were discussed at the international summit. ILE handling includes the preparation and the administration steps in the typical use of parenteral nutrition (PN). The discussion and consensus statements addressed several issues, including standardization of the PN process, use of commercially available multi‐chamber PN or compounded PN bags, the supervision by a pharmacist with expertise, limiting ILE repackaging, and infusion duration.

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How to perform appropriate flushing after lipid emulsion administration using totally implantable venous access devices in long-term total parenteral nutrition and home parenteral nutrition

Okamura

Yamato

Yamaoka

et al. 2021

Clinical Nutrition ESPEN

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Options available for the infusion of lipid emulsion in home parenteral nutrition (HPN): a questionnaire survey for hospitals in Japan where HPN is practiced

Cited by 4 publications

References 22 publications

Summary of Proceedings and Expert Consensus Statements From the International Summit “Lipids in Parenteral Nutrition”

Summary of Proceedings and Expert Consensus Statements From the International Summit “Lipids in Parenteral Nutrition”

Use of Intravenous Lipid Emulsions With Parenteral Nutrition: Practical Handling Aspects

How to perform appropriate flushing after lipid emulsion administration using totally implantable venous access devices in long-term total parenteral nutrition and home parenteral nutrition

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