Opto-Acoustic Transducers for Potentially Sensitive Ultrasonic Imaging

Wang, Keith; Burns, Vance; Wade, G.; Elliott, Scott S.

doi:10.1117/12.7972112

Cited by 11 publications

(3 citation statements)

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“…Extrapolating this publishing performance, a saturation of yearly publication output at about 9500 can be expected around 2030. After 30 years, it is interesting and important to benchmark this performance with other medical imaging techniques: 6 multiphoton microscopy (MPM) [including second harmonic generation (SHG) and third harmonic generation (THG)], developed about three decades before OCT, 7,8 has about 50,000 publications so far; photoacoustic imaging (PAI), established in the 1970s, 9,10 has about 15,000 papers; and confocal microscopy, developed in the 1940s, 11,12 has about 145,000. Developed in the 1940s, 13 US imaging has contributed to about 160,000 papers; positron emission tomography (PET), initiated in the 1970s, 14,15 has about 175,000; computed tomography (CT), developed in the 1930s, 16 has about 750,000; and magnetic resonance imaging (MRI), developed in the late 1940s, 17 has close to 1,000,000 publications.…”

Section: Introductionmentioning

confidence: 99%

Enhanced medical diagnosis for dOCTors: a perspective of optical coherence tomography

et al. 2021

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Significance: After three decades, more than 75,000 publications, tens of companies being involved in its commercialization, and a global market perspective of about USD 1.5 billion in 2023, optical coherence tomography (OCT) has become one of the fastest successfully translated imaging techniques with substantial clinical and economic impacts and acceptance.Aim: Our perspective focuses on disruptive forward-looking innovations and key technologies to further boost OCT performance and therefore enable significantly enhanced medical diagnosis.Approach: A comprehensive review of state-of-the-art accomplishments in OCT has been performed. Results:The most disruptive future OCT innovations include imaging resolution and speed (single-beam raster scanning versus parallelization) improvement, new implementations for dual modality or even multimodality systems, and using endogenous or exogenous contrast in these hybrid OCT systems targeting molecular and metabolic imaging. Aside from OCT angiography, no other functional or contrast enhancing OCT extension has accomplished comparable clinical and commercial impacts. Some more recently developed extensions, e.g., optical coherence elastography, dynamic contrast OCT, optoretinography, and artificial intelligence enhanced OCT are also considered with high potential for the future. In addition, OCT miniaturization for portable, compact, handheld, and/or cost-effective capsule-based OCT applications, home-OCT, and self-OCT systems based on micro-optic assemblies or photonic integrated circuits will revolutionize new applications and availability in the near future. Finally, clinical translation of OCT including medical device regulatory challenges will continue to be absolutely essential.Conclusions: With its exquisite non-invasive, micrometer resolution depth sectioning capability, OCT has especially revolutionized ophthalmic diagnosis and hence is the fastest adopted imaging technology in the history of ophthalmology. Nonetheless, OCT has not been completely exploited and has substantial growth potential-in academics as well as in industry. This applies not only to the ophthalmic application field, but also especially to the original motivation of OCT to enable optical biopsy, i.e., the in situ imaging of tissue microstructure with a resolution approaching that of histology but without the need for tissue excision.

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Section: Introductionmentioning

confidence: 99%

Enhanced medical diagnosis for dOCTors: a perspective of optical coherence tomography

et al. 2021

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“…Subsequently, Wang and Wade [Z] proposed to develop an aroustical transmitter based on the same principle for biomedical imaging and nondestructive testing. Several workers [3], [4] are currently in the development stages on devices of this type as either receivers or transmitters.…”

Section: Introductionmentioning

confidence: 99%

“…In order to investigate this behavior, an equivalent circuit for the case of a positive opto-acoustic transducer (P-OAT) [3] was recently developed (51.…”

Section: Introductionmentioning

confidence: 99%

An Improved Equivalent Circuit for Opto-Acoustic Transducers

Noorbehesht¹,

Wade²

1979

1979 Ultrasonics Symposium

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An opto-acoustic transducer (OAT) converts a spatial distribution of optical intensity into a corresponding distribution of acoustical amplitude. We recently presented a circuit model for the OAT which showed the switching ratio (the ratio of the acoustical pressure in the illuminated region to that in the dark region) to be an important characteristic of the device.The switching ratios predicted by that model, however, were found to be considerably higher than the values obtained experimentally. A l s o , the model predicted the switching ratio to be a rnonotonically increasing function of the thickness of the photoconductive layer, again contradictory to experimental observations. We have modified the original model by including optical absorption characteristics. The new model is better able to predict the maximum switching ratio obtainable. It also shows that under given operating conditions there exists an optimum thickness for the photoconductive layer for which the switching ratio is a maximum. The effects of various design parameters on the output can readily be calculated from the model.

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Fresnel Zone Plate and Fresnel Phase Plate Patterns for Acoustic Transducers

Mortezaie

Wade

1984

Acoustical Imaging

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Opto-Acoustic Transducers for Potentially Sensitive Ultrasonic Imaging

Cited by 11 publications

References 0 publications

Enhanced medical diagnosis for dOCTors: a perspective of optical coherence tomography

Enhanced medical diagnosis for dOCTors: a perspective of optical coherence tomography

An Improved Equivalent Circuit for Opto-Acoustic Transducers

Fresnel Zone Plate and Fresnel Phase Plate Patterns for Acoustic Transducers

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