Optoacoustic imaging and potential applications of raster-scan optoacoustic mesoscopy in dermatology

Messas, Tassahil; Messas, Achraf; Kroumpouzos, George

doi:10.1016/j.clindermatol.2021.12.001

Cited by 4 publications

(2 citation statements)

References 49 publications

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“…In this review, our objective is to narrow down the focus to the application of PAI in dermatology, a domain that has often been approached with a broader scope in previous literature [25][26][27][28][29][30][31]. Unlike previous reviews that predominantly focused on either photoacoustic microscopy (PAM) or photoacoustic computed tomography (PACT) [32][33][34][35], our review encompasses both modalities, offering a comprehensive overview of PAI applications in dermatology. By consolidating information on major PAI configurations and highlighting multiple clinical translation potentials, we aim to emphasize the unique role of PAI in addressing critical challenges in the diagnosis and treatment of skin cancer, psoriasis, and other dermatological conditions (Figure 1).…”

Section: Ultrasoundmentioning

confidence: 99%

Photoacoustic Imaging of Human Skin for Accurate Diagnosis and Treatment Guidance

Ying,

Zhang,

Lin

2024

Optics

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Photoacoustic imaging (PAI) is a cutting-edge biomedical imaging modality, providing detailed anatomical and functional information about the area beneath the skin surface. Its light energy deposition is such that PAI typically provides clear images of the skin with high signal-to-noise ratios. Specifically, the rich optical contrast of PAI allows biological information related to lesion growth, malignancy, treatment response, and prognosis to be seen. Given its significant advantages and emerging role in imaging skin lesions, we summarize and comment on representative studies of skin PAI, such as the guidance of skin cancer biopsies and surgical excisions, and the accurate diagnosis of psoriasis. We conclude with our insights about the clinical significance of skin PAI, showing how its use to identify biological characteristics in lesion microenvironments allows early diagnosis and prognosis of disease.

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Section: Ultrasoundmentioning

confidence: 99%

Photoacoustic Imaging of Human Skin for Accurate Diagnosis and Treatment Guidance

Ying,

Zhang,

Lin

2024

Optics

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“…This phenomenon allows us to measure specifically and deeply into the skin for features, such as blood vessels, blood oxygen saturation, and melanin, which are light‐absorbing substances. The method has been studied for melanoma 15 and other skin diseases, 16 , 17 but has not yet been studied for normal subjects. In this study, we aimed to analyze the individual differences and aging changes in the normal healthy skin by measuring the internal skin characteristics, such as vascular structure, oxygen saturation, and the 3D distribution of melanin in the epidermis, using a noninvasive PA measurement method.…”

Section: Introductionmentioning

confidence: 99%

Quantitative analysis of age‐related changes in vascular structure, oxygen saturation, and epidermal melanin structure using photoacoustic methods

Mizukoshi,

Iwazaki,

Ida

2024

Skin Research and Technology

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BackgroundVascular structure, blood oxygen saturation, and melanin status of the epidermis are chromophore factors related to light absorption. Therefore, they are likely to be related to skin appearance. Thus, it is important to measure these internal skin features and understand their characteristics. Thus, we aimed to analyze the individual differences and aging changes in the skin by measuring the internal skin characteristics, such as vascular structure, oxygen saturation, and the 3D distribution of melanin in the epidermis, using a noninvasive photoacoustic (PA) measurement method.Materials and MethodsA PA measurement device was used as a noninvasive measurement method. Eighty Japanese women aged between 20 and 60 years were enrolled. The target area was the buccal region of the face.ResultsThe blood vessel structure showed a decrease in fine vessels with age, with a stronger tendency observed in the dermis layer, and the volume of blood vessels was larger in the dermis layer than in the dermal–subcutaneous fat boundary layer. Oxygen saturation showed a similar decreasing trend with age in all depths examined. Melanin condition as the torus‐like pattern structure tended to increase with age.ConclusionPA measurements revealed the characteristics of several chromophores, providing a new skin aging mechanism.

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Further insight into systemic sclerosis from the vasculopathy perspective

Ren

Liu

Xiao

et al. 2023

Biomedicine & Pharmacotherapy

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Optoacoustic imaging and potential applications of raster-scan optoacoustic mesoscopy in dermatology

Cited by 4 publications

References 49 publications

Photoacoustic Imaging of Human Skin for Accurate Diagnosis and Treatment Guidance

Photoacoustic Imaging of Human Skin for Accurate Diagnosis and Treatment Guidance

Quantitative analysis of age‐related changes in vascular structure, oxygen saturation, and epidermal melanin structure using photoacoustic methods

Further insight into systemic sclerosis from the vasculopathy perspective

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