OR5. Ambulatory blood pressure profile among uncontrolled hypertensive patients in Indonesian Army Central Hospital Gatot Soebroto: an initial study

Abstract

Aims Ambulatory blood pressure monitoring (ABPM) has an important role in the evaluation of blood pressure (BP) control, particularly in uncontrolled hypertension, to optimize therapy. This study assessed ambulatory blood pressure profiles among patients with uncontrolled hypertension in Indonesian Army Central Hospital Gatot Soebroto. Methods and Results During our initial study from February to May 2021, a total of 40 patients with uncontrolled hypertension from Cardiac Outpatient Clinic, Indonesian Army Central Hospital Gatot Soebroto were recruited. Uncontrolled hypertension was defined as systolic BP >140 mmHg and or diastolic BP >90 mmHg in patients taking antihypertensive treatment. The population was 67.5% female, aged 63.18 + 11.82 years old, with an average office systolic BP of 157.5 + 24.41 mmHg and diastolic BP of 80.55 + 15.37 mmHg. All patients underwent ABPM within a week after the index office visit to evaluate 24-hour BP, BP variability, and white coat effect. The average 24-hour systolic and diastolic BP of the population was 137.40 + 16.7 mmHg and 78.55 + 12.94 mmHg respectively. Reverse-dipper was the most frequent pattern presented (47.5%). White coat effect was found in 47.5% of subjects and 27.5% of the total population were classified as white coat uncontrolled hypertension. Conclusion A marked discrepancy was found between ambulatory blood pressure profiles with office BP among patients with uncontrolled hypertension. Nearly half of the population had white coat effect, which revealed the importance of blood pressure control evaluation by ABPM to prevent overtreatment.