2023
DOI: 10.1292/jvms.23-0347
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Oral 5-aminolevulinic acid combined with sodium ferrous citrate prevents blood–aqueous barrier breakdown after anterior chamber paracentesis in healthy beagle dogs

Yuya OTAKA,
Kazutaka KANAI,
Aoi TOMATSU
et al.

Abstract: This study investigated the preventive effect of 5-aminolevulinic acid combined with sodium ferrous citrate (5-ALA/SFC) on blood–aqueous barrier (BAB) breakdown induced after anterior chamber paracentesis (ACP) in beagles. 5-ALA/SFC (1/0.64 mg/kg or 3/1.92 mg/kg) or carprofen (4.0 mg/kg) was orally administered daily for 7 days prior to ACP. Then, a sample of the aqueous humor (AH) was collected from one eye via ACP (first sample) and again 60 min later (second sample). The protein and prostaglandin E2 (PGE2) … Show more

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