Oral administration of analgesia and anxiolysis for pain associated with bone marrow biopsy

Abstract

An oral administration of prophylactic regimen of analgesia and anxiolysis, at the above-mentioned doses, produced a statistically significant reduction of the perception of pain in patients undergoing BMAB, but its effect did not seem to provide a major and clinically significant reduction of pain level.

Children's discomfort in assessments using different methods for approximal caries detection

“…Furthermore, it is a reliable tool that has been translated into several languages and is extensively employed to evaluate pain and discomfort for a variety of clinical procedures. 13,17,18 Previous studies have compared different methods of pain and discomfort assessment for children. Although these methods presented similar validity and reliability scores, the acceptance by children was higher with the Wong-Baker scale.…”

Procedural Care for Adult Bone Marrow Aspiration and Biopsy

“…3,6,24 In particular, there are few articles that provide guidance to practitioners for adult patients who are suffering from pain and anxiety associated with BMABs. 6,25 Indeed, there are no formal guidelines 'in the medical literature for the use of analgesia and anxiolysis (medications that help to reduce anxiety) before BMABs. 25 Clinical and procedural approaches vary among clinics and individual physicians and are without a consistent strategy.…”

“…6,25 Indeed, there are no formal guidelines 'in the medical literature for the use of analgesia and anxiolysis (medications that help to reduce anxiety) before BMABs. 25 Clinical and procedural approaches vary among clinics and individual physicians and are without a consistent strategy. 25 In view of the present findings, the lack of empirical research to base best practice on is of grave concern.…”

Clinical Aspects of Regenerative Medicine

“…Alternatively, an automated power driver (Figure 3) may be used for decreasing the duration of the marrow draw and less residual patient pain, although the latter remains unproven [69][70][71]. Use of acetaminophen/hydrocodone, tramadol, or diazepam preprocedure has been shown to be effective in reducing patient pain scores [72]. With proper technique and patient care, general anesthesia is not warranted, and most patients tolerate the marrow aspiration well.…”