Oral administration of Lactobacillus plantarum strain Lq80 to weaning piglets stimulates the growth of indigenous lactobacilli to modify the lactobacillal population

Takahashi, Shunsuke; Egawa, Yayoi; Simojo, Nobuyuki; Tsukahara, Takamitsu; Ushida, Kazunari

doi:10.2323/jgam.53.325

Cited by 30 publications

(18 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Isolates grown in the TOS-propionate broth medium were recovered to analyze their 16S rDNA (from 27 to 1492, E. coli position) according to methods described elsewhere (Takahashi et al, 2007).…”

mentioning

confidence: 99%

Isolation of Bifidobacteria from feces of chimpanzees in the wild

Ushida

Uwatoko

Adachi

et al. 2010

J. Gen. Appl. Microbiol.

Self Cite

View full text Add to dashboard Cite

mentioning

confidence: 99%

Isolation of Bifidobacteria from feces of chimpanzees in the wild

Ushida

Uwatoko

Adachi

et al. 2010

J. Gen. Appl. Microbiol.

Self Cite

View full text Add to dashboard Cite

“…L. plantarum is found in fermented food products derived from plant material and is also a natural inhabitant of the human gut [4, 25,26,27,28,29]. However, previous studies reported no detectable levels of L. plantarum naturally occurring in the gut of piglets [30] or mice [16, 17]. We therefore suspected that L. plantarum might be adapted to the gastrointestinal tract of humans but not to those of other animals.…”

Section: Discussionmentioning

confidence: 99%

Persistence of Orally Administered <i>Lactobacillus</i> Strains in the Gut of Infant Mice

Ozawa

Fujiwara

Watanabe

et al. 2012

Bioscience of Microbiota, Food and Health

View full text Add to dashboard Cite

The present study tested the persistence of orally administered bacteria in the gut of suckling mice. We used three bacterial strains: one strain of Lactobacillus johnsonii (designated strain Ms1) that was previously isolated from the mouse stomach, and two strains of L. plantarum, (strain No. 14 and JCM 1149T). We detected L. johnsonii Ms1, but neither strain of L. plantarum, in the gut 7 days after administration when the organisms were administered on days 0, 1, 3 or 7 of neonatal life. None of the strains was detected in the gut 7 days after the administration on days 14 or 28 of neonatal life. L. johnsonii Ms1 and L. plantarum JCM 1149T exhibited similar levels of in vitro association with gut tissues, with both strains showing association that was significantly higher than that of L. plantarum No. 14. In a separate experiment, the number of total bacteria and lactobacilli in the gut, as estimated by real-time quantitative PCR, was significantly higher in 14- and 21-day-old mice than in 0- and 7-day-old mice. In addition, the number of total bacteria was higher in 21-day-old mice than in 14-day-old mice, and the number of lactobacilli was higher in 7-day-old mice than in 0-day-old mice. These results suggest that gut persistence of administered bacteria in infant mice is species- or strain-specific and is affected by the development of indigenous microbiota. In addition, gut persistence of administered bacteria may not always depend on the tissue association capacity.

show abstract

“…Furthermore, the FLD might directly affect the composition of the gastrointestinal microbiota. In fact, the composition of fecal lactobacilli was markedly altered by an oral administration of LQ80 (Takahashi et al, 2007). Therefore, the FLD containing LQ80 may affect the systemic immune response via a modulation of intestinal microbiota.…”

Section: Discussionmentioning

confidence: 99%

“…It has been known that these organisms are capable of living in the gut when they are orally administered (Takahashi et al, 2007). We tested the ability of this bacterium to stimulate IFN-g and IL-6 production from the blood cells of piglets by co-culturing the blood cells with live and heat-treated bacteria.…”

Section: Growth Performancementioning

confidence: 99%

Effect of fermented liquid diet prepared with Lactobacillus plantarum LQ80 on the immune response in weaning pigs

Mizumachi

Aoki

Ohmori

et al. 2009

Animal

View full text Add to dashboard Cite

Probiotics such as lactic acid bacteria directly influence the host's health and have beneficial effects such as decreasing the number of enteric pathogens, regulating intestinal immune responses and preventing diseases. Among domestic animals, probiotics have been expected to be an alternative to antibiotics added in the diet; and fermented liquid diet (FLD) containing probiotics has great potential as a diet for reducing the use of antibiotics. In this study, we evaluated the immunomodulatory effects of FLD, prepared using Lactobacillus plantarum LQ80 (LQ80), on the immune response of weaning pigs. Ten weaning piglets were divided into two groups and were fed the FLD (n 5 5) or a non-fermented liquid diet (NFLD) (n 5 5) for 28 days. At the end of the experiment, the total immunoglobulin M (IgM) and immunoglobulin G (IgG) levels in the sera of the FLD-fed piglets were significantly higher than those of the NFLD-fed piglets ( P , 0.05). In contrast, the total immunoglobulin A (IgA) levels in the feces and saliva were not significantly affected by FLD feeding. However, the mean fecal IgA levels of FLD-fed piglets at day 28 were higher than those at 14 and 21 days ( P , 0.05). Blood cells from the FLD-fed piglets showed a low level of interferon-g secretion and mitogen-induced proliferation compared to that of the NFLD-fed piglets. Furthermore, the levels of interluekin-8 and tumor necrosis factor-a, which are proinflammatory cytokines, in the blood cells of the FLD-fed piglets were lower than those of the NFLD-fed piglets ( P , 0.05). In conclusion, the FLD used in this study could alter the immune responses of weaning piglets by stimulation of the systemic or mucosal antibody response, without unnecessary inflammatory reactions. This indicates, that the FLD feed prepared with the use of LQ80 may be a candidate feed, with regard to enhancing immune responses and preventing diseases in weaning piglets.

show abstract

Oral administration of Lactobacillus plantarum strain Lq80 to weaning piglets stimulates the growth of indigenous lactobacilli to modify the lactobacillal population

Cited by 30 publications

References 28 publications

Isolation of Bifidobacteria from feces of chimpanzees in the wild

Isolation of Bifidobacteria from feces of chimpanzees in the wild

Persistence of Orally Administered <i>Lactobacillus</i> Strains in the Gut of Infant Mice

Effect of fermented liquid diet prepared with Lactobacillus plantarum LQ80 on the immune response in weaning pigs

Contact Info

Product

Resources

About