Oral and maxillofacial cancer: A 35-year retrospective analysis at a referral dental hospital in Saudi Arabia

The role of radiotherapy in the treatment of malignant tumors of the oral and maxillofacial region

“…Najčešće lokalizacije ovih tumora su gingiva, jezik, bukalna sluznica, usta, nepce, maksila, parotida i sinusi. Histološki tipovi koji su zastupljeni u ovoj regiji su skvamocelularni i mukoepidermiodni karcinom, osteosarkom, limfom i melanom [2]. Savremena klasifikacija SZO (Svetska zdravstvena organizacija) deli ih na: benigne i maligne odontogene tumore, benigne i maligne tumore kostiju i hrskavice, benigne i maligne tumore mekih tkiva, fibro-koštane i hematolimfoidne tumore [3].…”

“…The most common localizations of these tumors are gingiva, tongue, buccal mucosa, mouth, palate, maxilla, parotid gland and sinuses. Histological types represented in this region are squamous cell and mucoepidermoide carcinoma, osteosarcoma, lymphoma, and melanoma [2]. The current WHO (World health organisation) classification divides them into benign and malignant odontogenic tumors, benign and malignant tumors of bone and cartilage, benign and malignant soft tissue tumors, fibrose and bone tumors and hematolymphoid tumors [3].…”

Oral Cancer Staging and Clinicopathologic Features Presenting to Oral & Maxillofacial Surgery Practice in Saudi Arabia

“…Oral cancer is more prevalent in Saudi Arabia than in surrounding Gulf countries, such as Kuwait and the United Arab Emirates, which share similar geographical and cultural characteristics. [7] Approximately 26 percent of all head and neck cancers detected annually in KSA are oral cancers, most of which are in advanced stages requiring palliative care. [8] Several studies have shown that the use of Shamma, a form of smokeless tobacco, is associated with the high incidence of oral cancer mentioned earlier.…”

“…[8] Several studies have shown that the use of Shamma, a form of smokeless tobacco, is associated with the high incidence of oral cancer mentioned earlier. [7,9] The survival rate of oral cancer is one of the lowest in the world. Despite the ease with which malignant lesions may be detected in the oral cavity, it is unfortunate that a significant number of oral cancer cases are discovered at an advanced stage.…”

“…According to a meta-analysis, diagnosis delay was likely to be a contributing factor to advanced-stage OC and mortality. [7,10] The survival rate for oral squamous cell carcinoma has only marginally improved despite advancements in imaging techniques (including computed tomography, positron emission tomography, magnetic resonance imaging, and ultrasound), surgical techniques, radiation therapy sources and delivery methods, and combination with chemotherapy. [11,12] Many patients who have had successful treatment for oral cancer may experience functional and cosmetic impairments, including difficulties eating, swallowing, speaking, and disfigurement which may have a significant adverse impact on their quality of life.…”