Oral and Maxillofacial Manifestations of Mineral and Bone Disorders Associated with Chronic Renal Failure

The aim of study was to investigate the relationship between oral health and nutritional status in a population of elderly patients with systemic chronic or acute pathology. Materials and method: Prospective cross-sectional clinical investigation of 115 aged patients (] 60 yo; mean age 66.2) from the Clinical Foundation, Faculty of Dental Medicine, University of Medicine and Pharmacy of Iasi. In the first stage of the study, the patients (able to understand and communicate) were submitted to a mini-test for the assessment of the mental status (MMSE) . In the second stage of the study, a questionnaire was used to record demographic and socioeconomic data of the subjects as well as information regarding systemic status and nutritional facts. In the third stage of the study, the nutritional status was evaluated by using Mini-Nutritional Assessment questionnaire (MNA). Finally, the oral status was evaluated by using clinical and radiographical exams as well as geriatric oral health assessment index (GOHAI). Results: Of the 60 old adults, 6% were severely malnourished, and 37.4% presented malnourished risk. 49.6% of the old people had difficulties eating firm foods, 25% of them being unable to prepare meals. Regarding oral status, only 5.2% had at least 20 natural teeth, 55.6% required dental care for decayed or broken teeth, 69.6% were affected by xerostomia, 21% of the completely or partial edentulous people were untreated by removable dentures, 25% of the edentulous patients complained by ill-fitted removable dentures. Conclusion: Lack of education, treatment with over 3 drugs daily, physical inability to buy foods or to prepare meals, as well as the difficulties eating firm foods are strongly associated with poor nutritional status. Also, the need for dental care was associated to nutritional deficiency.

Section: Resultsmentioning

confidence: 99%

Study Regarding the Relationship between Nutritional Status and Oral Health in the Elderly Patients

Surdu¹,

Bobu²,

Cioloca³

et al. 2019

“…Side (horizontal) and rotation forces are more likely to injure periodontitis. The response of the alveolar bone is also affected by the duration and frequency of occlusal forces [7]. Constant bone pressure is more damaging than intermittent forces.…”

Section: Abstract: Rankl Chronic Periodontitis Occlusal Traumamentioning

confidence: 99%

ELISA Evaluation of RANKL Levels in Gingival Fluid in Patients with Periodontitis and Occlusal Trauma

Popa¹,

Luchian²,

Ioanid³

et al. 2018

The aim of this study was to evaluate the differences in RANKL levels in crevicular fluid (GCF) in patients with chronic periodontitis, with or without chronic occlusal trauma. The study group consisted of 40 patients from whom 72 samples of crevicular fluid were collected. RANKL levels were analyzed by ELISA. We noticed significantly higher differences in RANKL levels for the study group (occlusive trauma patients) than for systemic healthy patients (p = 8.008). Research has shown that secondary occlusal trauma associated with periodontal disease is characterized by significantly higher RANKL levels in patients with chronic occlusal trauma. This partially clarifies the molecular mechanisms that underlie more severe tissue destruction in patients with occlusal trauma.

“…This is the case for short-chain barbiturates, glutetimide and fenbulasone. The management of anti-inflammatory drugs is based on a half-life strategy (1/2) [23][24][25][26][27][28][29][30][31][32][33][34] Acetylsalicylic acid -Aspirine…”

mentioning

confidence: 99%

General and Particular Structural Characteristics of Acetylsalicylic Acid - Aspirine Chemical properties

Topor¹,

Nechita²,

Debita³

et al. 2019

Anti-inflammatory-analgesic medication is known to have a wide spread, its indications going beyond the area of rheumatology, aimed at various fields, cardiology, nephrology, hematology,neurology, etc. Many years of aspirin has constituted the health expectation of millions of patients. Most nonsteroidal anti-inflammatory analgesics (ASNS) are acidic compounds derived mainly from carboxylic acids and enolic acids. The non-acidic compounds are numerically reduced and relatively unrelated. The main effects of non-steroidal anti-inflammatory analgesics arise following antipyretic action, analgesic action and anti-immflamatory in varying proportions to each structural group. Each drug has the specificity of single actions, the global way of explaining the clinical effects remains little known. Anti-inflammatory (anti-termic) in acute rheumatism or other inflammatory joint disorders, anti-platelet antiaggregant, aspirin prevents aggregation of blood platelets (which have a role in stopping bleeding).This is why it is used to prevent thrombosis (clotting of blood in the arteries or veins) with an impOliant role in preventing myocardial infarction. The study includes 126 patients who often used aspirin. Interaction of aspirin with other drugs mainly occurs in the plasma albumin, platelets, liver, kidney and gastrointestinal tract. Considered a common drug, often used by patients without the physician�s indication, some of them under maintenance medication (corticosteroid, anticoagulants, antiplatelet, antidiabetics, cytostatics), aspirin may cause important complications.