Oral bait preferences and feasibility of oral rabies vaccination in Bangladeshi dogs

Bonwitt, Jesse; Bonaparte, Sarah; Blanton, Jesse D.; Gibson, Andrew D; Hoque, Mahbub; Kennedy, Erin D.; Islam, Kamrul; Siddiqi, Umme Ruman; Wallace, Ryan M.; Azam, Shakif

doi:10.1016/j.vaccine.2020.05.047

Cited by 17 publications

(20 citation statements)

References 12 publications

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“…Baits which are too small and are swallowed without perforating the sachet will not be immunized. Numerous studies have performed to evaluate preference for different bait casing materials, including fishmeal, animal intestine, chicken head, egg and dog food based materials [59][60][61][62][63][64][65]. There was considerable variation in the preference for different bait materials by location, possibly reflecting the normal diet of the population.…”

Section: Oral Rabies Vaccination Of Dogsmentioning

confidence: 99%

“…There was considerable variation in the preference for different bait materials by location, possibly reflecting the normal diet of the population. Studies in India, Bangladesh and Thailand all reported high rates of uptake and perforation in egg-based bait constructs [59,63,66]. Egg-based bait constructs also have the benefit of being broadly culturally acceptable and offering potential for mass-production with basic production facilities.…”

Section: Oral Rabies Vaccination Of Dogsmentioning

confidence: 99%

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Review of Oral Rabies Vaccination of Dogs and Its Application in India

Yale

Lopes

Isloor³

et al. 2022

Viruses

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Oral rabies vaccines (ORVs) have been in use to successfully control rabies in wildlife since 1978 across Europe and the USA. This review focuses on the potential and need for the use of ORVs in free-roaming dogs to control dog-transmitted rabies in India. Iterative work to improve ORVs over the past four decades has resulted in vaccines that have high safety profiles whilst generating a consistent protective immune response to the rabies virus. The available evidence for safety and efficacy of modern ORVs in dogs and the broad and outspoken support from prominent global public health institutions for their use provides confidence to national authorities considering their use in rabies-endemic regions. India is estimated to have the largest rabies burden of any country and, whilst considerable progress has been made to increase access to human rabies prophylaxis, examples of high-output mass dog vaccination campaigns to eliminate the virus at the source remain limited. Efficiently accessing a large proportion of the dog population through parenteral methods is a considerable challenge due to the large, evasive stray dog population in many settings. Existing parenteral approaches require large skilled dog-catching teams to reach these dogs, which present financial, operational and logistical limitations to achieve 70% dog vaccination coverage in urban settings in a short duration. ORV presents the potential to accelerate the development of approaches to eliminate rabies across large areas of the South Asia region. Here we review the use of ORVs in wildlife and dogs, with specific consideration of the India setting. We also present the results of a risk analysis for a hypothetical campaign using ORV for the vaccination of dogs in an Indian state.

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Section: Oral Rabies Vaccination Of Dogsmentioning

confidence: 99%

Section: Oral Rabies Vaccination Of Dogsmentioning

confidence: 99%

Review of Oral Rabies Vaccination of Dogs and Its Application in India

Yale

Lopes

Isloor³

et al. 2022

Viruses

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Section: Outcome 12 Rabies Is Prevented Through Increased and Effective Dog Vaccinationmentioning

confidence: 99%

“…Five studies assessed the use of Oral Rabies Vaccination (ORV) in India, Thailand, and Bangladesh to reach freeroaming dogs that are not captured by routine parenteral vaccination [64][65][66][67][68]. These studies were focused on the establishment of preferred baits [64,68], and their potency following consumption [65][66][67]. ORV also fared well compared to Capture, Vaccinate and Release (CVR) strategies for reaching free-ranging dogs in terms of the percentage of dogs reached and implementation logistics [65].…”

Section: Outcome 12 Rabies Is Prevented Through Increased and Effective Dog Vaccinationmentioning

confidence: 99%

“…Problems reported on coverage estimation included initial dog population estimates being lower than total dogs subsequently vaccinated [25] and counting only owned dogs without including free-roaming animals that are more likely to transmit rabies [50,69]. Likewise, difficulties were reported in how to mark dogs for estimating coverage when conducting ORV [64,65]. Studies of parenteral vaccination in Kenya [27] and Tanzania [70] also reported that different techniques of estimating dog populations resulted in different levels of estimated coverage.…”

Section: Outcome 12 Rabies Is Prevented Through Increased and Effective Dog Vaccinationmentioning

confidence: 99%

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Human rabies: prospects for elimination

et al. 2021

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Almost half of all countries in the world are effectively free of human deaths from dog-mediated rabies. But the disease still affects people in low- and middle-income countries, especially the rural poor, and children. Successful regional elimination of human rabies is attributable to advances in significant and sustained investment in dog vaccination, post-exposure vaccination and surveillance, illustrated by productive efforts to reduce human rabies in Latin America over the last 35 years. Nonetheless, countries still facing endemic rabies face significant barriers to elimination. Using the 2017 Global Strategic Plan to end human rabies deaths from dog-mediated rabies by 2030 as a reference point and an organizing framework, we assess progress toward global rabies elimination by examining the characteristics of successful regional control efforts and barriers to elimination. Although substantive barriers exist for countries where rabies remains endemic, advances in knowledge, technology, institutions, and economics provide a basis for optimism.

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Rabies

Acharya,

Phuyal

2025

Neglected Zoonoses and Antimicrobial Resistance

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Oral bait preferences and feasibility of oral rabies vaccination in Bangladeshi dogs

Cited by 17 publications

References 12 publications

Review of Oral Rabies Vaccination of Dogs and Its Application in India

Review of Oral Rabies Vaccination of Dogs and Its Application in India

Human rabies: prospects for elimination

Rabies

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