Oral behavior, dental, periodontal and microbiological findings in patients undergoing hemodialysis and after kidney transplantation

Abstract

BackgroundAim of this single center cross-sectional study was to investigate oral behavior, dental, periodontal and microbiological findings in patients undergoing hemodialysis (HD) and after kidney transplantation (KT).MethodsPatients undergoing HD for end-stage renal failure and after KT were investigated. Oral health behavior was recorded using a standardized questionnaire, e.g. dental behavior, tooth brushing, oral hygiene aids. Oral investigation included screening of oral mucosa, dental findings (DMF-T) and periodontal situation (Papilla bleeding index [PBI] periodontal probing depth [PPD] and clinical attachment loss [CAL]). Additionally, microbiological analysis of subgingival biofilm samples (PCR) was performed. Statistical analysis: Student’s t-test or Mann–Whitney-U-test, Fisher’s exact test (α = 5 %).ResultsA total of 70 patients (HD: n = 35, KT: n = 35) with a mean age of 56.4 ± 11.1 (HD) and 55.8 ± 10.9 (KT) years were included. Lack in use of additional oral hygiene (dental floss, inter-dental brush) was found. KT group presented significantly more gingivial overgrowth (p = 0.01). DMF-T was 19.47 ± 5.84 (HD) and 17.61 ± 5.81 (KT; p = 0.21). Majority of patients had clinically moderate and severe periodontitis; showing a need for periodontal treatment of 57 % (HD) and 71 % (KT; p = 0.30). Significantly higher prevalence of Parvimonas micra and Capnocytophaga species in the HD group were found (p < 0.01).ConclusionPeriodontal treatment need and lack in oral behavior for both groups indicate the necessity of an improved early treatment and prevention of dental and periodontal disease, e.g. in form of special care programs. Regarding microbiological findings, no major differences between KT and HD patients were found.

Deficits in oral health behavior and oral health status in patients after lung transplantation

“…26 DMF-T findings for LTx recipients in our study were similar to those for older senior citizens from the general German population in the DMS IV and higher compared with the DMS V. 27 The DMF-T was nearly identical but the F-T was slightly higher and M-T slightly lower. 20 When compared with a group of different solid organ transplant recipients with a mean age of 53.9 years 18 and with the patients after kidney transplantation in a study by Schmalz et al with a mean age 45.7 years, 28 our LTx patients had higher DMF-T values which resulted mainly from the high M-T values.…”

The directional and non‐directional associations of periodontitis with chronic kidney disease: A systematic review and meta‐analysis of observational studies

“…Table describes the characteristics of 7 case‐control studies and 38 cross‐sectional studies on the non‐directional association, and lists them in reverse publication order . Among them, 24 had a statistical analysis, but 7 did not consider any confounding factors (Appendix A) .…”

Oral health related quality of life depending on oral health and specific factors in patients after lung transplantation

“…1,2 In this context, also oral health might play a key role, as a recent review article points the association between oral health, especially periodontal inflammation, and respiratory diseases. [7][8][9] The potential reasons for this unsatisfactory situation might be various and complex. [4][5][6] In contrast, recent investigations on the oral health situation of transplant recipients show insufficient dental and periodontal health, as well as shortcomings in dental behavior of patients after solid organ transplantation, including lung, liver, and kidney.…”

“…3 Beside of that special condition, patients after organ transplantation in general should be early dental rehabilitated and the demand of a sufficient maintenance is present in literature. [7][8][9] In this respect, the oral health related quality of life (OHRQoL), which is a part of the general health related QoL 10 might be of relevance. [7][8][9] The potential reasons for this unsatisfactory situation might be various and complex.…”