2015
DOI: 10.1016/j.oraloncology.2014.11.008
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Oral Candida colonization in oral cancer patients and its relationship with traditional risk factors of oral cancer: A matched case-control study

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Cited by 128 publications
(131 citation statements)
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“…Previous studies have demonstrated a significant association between ABC genotyping and the virulence potential of C. albicans strains (Qianming et al , ; Zeng et al , ; Sardi et al , ). In our previous investigation, a significant epidemiological relationship was found between oral cancer presence and C. albicans genotype (Alnuaimi et al , ). Specifically, a significantly higher frequency of genotype A was observed in C. albicans strains isolated from patients with oral cancer and significantly higher frequency of genotype B was seen in patients with non‐oral cancer.…”
Section: Discussionmentioning
confidence: 82%
“…Previous studies have demonstrated a significant association between ABC genotyping and the virulence potential of C. albicans strains (Qianming et al , ; Zeng et al , ; Sardi et al , ). In our previous investigation, a significant epidemiological relationship was found between oral cancer presence and C. albicans genotype (Alnuaimi et al , ). Specifically, a significantly higher frequency of genotype A was observed in C. albicans strains isolated from patients with oral cancer and significantly higher frequency of genotype B was seen in patients with non‐oral cancer.…”
Section: Discussionmentioning
confidence: 82%
“…Genotypic variation exists in C. albicans strains between oral cancer and non-oral cancer patients. 25 Further analysis of strain genotypes is required, such as via PCR, to elucidate whether the phenotypic and genotypic attributes of Candida found in smokers and patients with active caries are different to those without these risk factors. A reflective profile of Candida found in oral cancer patients would be significant.…”
Section: Discussionmentioning
confidence: 99%
“…It is considered a global health issue affecting a wide portion of individuals in the population, such as newborns (Ali et al 2012), oral cancer patients (Alnuaimi et al 2015), denture wearers (Dar-Odeh & Shehabi 2003), among others, presenting different clinical features. Recently, oral candidiasis has also been reported to be a risk factor for disseminated bacterial infections, which constitute a critical and life-threatening trait, particularly in immunocompromised individuals (Kong et al 2015).…”
Section: Introductionmentioning
confidence: 99%