Oral Care Reduces Incidence of Ventilator-Associated Pneumonia in ICU Populations

Mori, Hideo; Hirasawa, Hiroyuki; Oda, Shigeto; Shiga, Hidetoshi; Matsuda, Kazuo; Nakamura, Masataka

doi:10.1007/s00134-005-0014-4

Cited by 192 publications

(169 citation statements)

References 32 publications

Supporting

Mentioning

134

Contrasting

Unclassified

Order By: Relevance

“…10 Oropharyngeal colonization with potentially pathogenic microorganisms is crucial in the pathogenesis of VAP. Oral care regimens that improve oral health status and modulate bacterial overgrowth could reduce the development of nosocomial VAP.…”

mentioning

confidence: 99%

Oral Care Interventions and Oropharyngeal Colonization in Children Receiving Mechanical Ventilation

Kusahara

Carvalho

Núñez

et al. 2009

American Journal of Critical Care

View full text Add to dashboard Cite

Background Recent progress in identification of oral microorganisms has shown that the oropharynx can be a site of origin for dissemination of pathogenic organisms to distant body sites, such as the lungs. Objective To compare the oropharyngeal microbiological profile, duration of mechanical ventilation, and length of stay in the intensive care unit of children receiving mechanical ven ti lation who had pharmacological or nonpharmacological oral care. Methods A randomized and controlled study was performed in a pediatric intensive unit in São Paulo, Brazil. A total of 56 children were randomly assigned to an experimental group (n = 27, 48%) that received oral care with use of 0.12% chlorhexidine digluconate or a control group (n = 29, 52%) that received oral care without an antiseptic. Oropharyngeal secretions were collected and cultured on days 0, 2, and 4, and at discharge. Results The 2 groups had similar demographic characteristics, preexisting underlying diseases, and pharmacological, nutritional, and ventilatory support. Gram-negative bacteria were the predominant pathogens: Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Enterobacter species. The 2 groups did not differ significantly in the colonization of normal (P = .72) or pathogenic (P = .62) flora, in the duration of mechanical ventilation (P = .67), or in length of stay in the intensive care (P = . Notice to CE enrollees:A closed-book, multiple-choice examination following this article tests your under standing of the following objectives:1. Describe the incidence of ventilator-associated pneumonia in the pediatric intensive care unit (PICU) patient population.2. Identify microorganisms that commonly colonize the oropharynx of PICU patients.3. Recognize the impact of an oral care routine using chlorhexidine on a PICU study group.

show abstract

mentioning

confidence: 99%

Oral Care Interventions and Oropharyngeal Colonization in Children Receiving Mechanical Ventilation

Kusahara

Carvalho

Núñez

et al. 2009

American Journal of Critical Care

View full text Add to dashboard Cite

show abstract

“…In a nonrandomized trial, 1248 patients in a medical-surgical ICU received oral care with a toothbrush and povidone-iodine swab. 21 Neuroscience patients accounted for 3% of the study population, but patients undergoing ICP monitoring were not identified. In the one study in which ICP was recorded during unspecified oral care (tooth brushing or swabs), ICP was stable in 879 recordings among patients with ICP values less than 20 mm Hg.…”

Section: Discussionmentioning

confidence: 99%

Electric Versus Manual Tooth Brushing among Neuroscience ICU Patients: Is it Safe?

2011

View full text Add to dashboard Cite

show abstract

“…In recent years, oral care has been shown to be effective in the prevention of pulmonary infections, including aspiration pneumonia (Segers et al, 2008; Of these cases, because contamination of the oral cavity or pharynx in patients receiving artificial respiration can lead to Ventilator-Associated Pneumonia (VAP), a serious form of pneumonia, the importance of oral care during the acute phase has become widely known (Feider et al, 2010;Hutchins et al, 2009;Mori et al, 2006). Because perioperative artificial respiration is a commonly performed procedure, prevention of VAP is a major issue for the general care of patients.…”

Section: Introductionmentioning

confidence: 99%

Factor Analysis on Onset of Ventilator-Associated Pneumonia for Inpatients in the Intensive Care Unit

Ooka

Okamatsu

Ando³

et al. 2015

Current Research in Dentistry

View full text Add to dashboard Cite

Abstract:The objective of the present study is toassess risk factors" at the stage of proofs, including oral health status, with the development of VAP in perioperative patients, with the final aim of the establishing oral health management systems in acute care hospitals. Of the patients who were admitted to the Intensive Care Unit (ICU) of our university hospital from January to December 2011 and who underwent oral intubation, 11 patients who received a diagnosis of VAP (nine men and two women) and 11 control patients (eight men and three women) were selected as subjects for the present study. We first investigated the disease names listed in the medical records of subjects in the VAP group and then selected patients who had the same diseases as the control group subjects. Within one day after admission to the ICU, a dentist evaluated the oral health status of the patients and the lips, teeth, oral mucosa, gingiva, tongue and xerostomia were scored (0-12) based on the criteria of the Revised Oral Assessment Guide (ROAG). Furthermore, six items (operative duration, BMI, length of ICU stay, Acute Physiology and Chronic Health Evaluation (APACHE II) score and length of ventilator used) were extracted from patient medical records and investigated. The items were used as independent variables and their relationship with the development of VAP was examined by regression analysis. Oral health care was performed by a nurse four times per day, using a standard toothbrush or sponge brush. Moreover, this study was approved by the Ethics Committee of the Department of Dentistry in our university. When each factor was compared in the VAP group and the control group, the VAP group showed significantly higher scores for oral health status, length of ICU stay and length of ventilator used. Furthermore, when the development of VAP and the relationships with each factor were examined by regression analysis, a significant relationship with oral health status, operative duration, BMI and length of ventilator use was seen. The results of the present study suggest the possibility of various factors being involved in the development of VAP in orally intubated patients, such as the oral health status of the patient. Appropriate oral health care can aid the prevention of perioperative pulmonary infections.

show abstract

Oral Care Reduces Incidence of Ventilator-Associated Pneumonia in ICU Populations

Abstract: Pulmonary nosocomial infection.

Cited by 192 publications

References 32 publications

Oral Care Interventions and Oropharyngeal Colonization in Children Receiving Mechanical Ventilation

Oral Care Interventions and Oropharyngeal Colonization in Children Receiving Mechanical Ventilation

Electric Versus Manual Tooth Brushing among Neuroscience ICU Patients: Is it Safe?

Factor Analysis on Onset of Ventilator-Associated Pneumonia for Inpatients in the Intensive Care Unit

Contact Info

Product

Resources

About