Oral exposure to high concentrations of polystyrene microplastics alters the intestinal environment and metabolic outcomes in mice
Yuka Hasegawa,
Takuro Okamura,
Yuriko Ono
et al.
Abstract:IntroductionOral exposure to microplastics (MPs) is a global health concern. In our previous study, MPs induced glucose intolerance and non-alcoholic fatty liver disease (NAFLD) under a high-fat diet-induced leaky gut syndrome (LGS). This study aims to evaluate the effects of high concentrations of MP on lipid metabolism under normal dietary conditions and to assess the changes in the intestinal tract resulting from MP exposure.MethodsC57BL6/J mice were fed a normal diet (ND) without polystyrene MPs (PS-MPs) o… Show more
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