Oral extramedullary plasmacytoma in a HIV positive patient

Shetty, Prashanth; Lobo, Flora D.; Arvind, R; Shetty, Sameep S.

doi:10.1016/j.oraloncology.2016.11.007

Cited by 3 publications

(2 citation statements)

References 7 publications

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“…There are only few reports of extramedullary plasmacytoma in HIV-positive patients published in the literature, including those involving the kidney, testis, adrenal, and oral cavity [8][9][10][11][12]. Hematolymphoid tumors are a subset of HIV-related malignancies which are acquired immunodeficiency syndrome (AIDS)defining malignancies.…”

Section: Discussionmentioning

confidence: 99%

Plasmacytoma of the Eyelid in an HIV-Positive Patient

Ramadan¹,

Kassa²

2021

J Opht Res Rev Rep

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Extramedullary (extraosseous) plasmacytoma represents a rare disease that accounts for less 5% of plasma cell neoplasms. It commonly occurs in the upper respiratory tract, with 80% of cases involving the paranasal sinuses, nasopharynx, or nasal cavity. Plasmacytomas of the eyelid are very rare with only ten cases having been reported in the literature so far. We present the clinical and histopathologic findings from a case of plasmacytoma of the eyelid and discuss its histopathologic differential diagnoses. To our knowledge, this is the first case of plasmacytoma of the eyelid in an HIV-positive patient in the English literature

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Section: Discussionmentioning

confidence: 99%

Plasmacytoma of the Eyelid in an HIV-Positive Patient

Ramadan¹,

Kassa²

2021

J Opht Res Rev Rep

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“…In paraskeletal oral lesions, patients will present with a large mass of the maxillary or mandibular alveolar ridge, with the overlying gingiva and mucosa ranging from pink and healthy in appearance to erythematous, ulcerated or necrotic. [ 5 - 7 ] For true extramedullary lesions without underlying bony involvement, lesions have been reported in the gingiva, buccal mucosa, labial mucosa, tongue and uvula. [ 8 , 9 ] One report described an extramedullary plasmacytoma that presented as a flat, non-tender erythematous macule, or erythroplakia, of the soft palate.…”

Section: Discussionmentioning

confidence: 99%

Extramedullary Plasmacytomas of the Oral Cavity: A Case Report and Review of the Literature

Bavarian

Treister

2021

J Cancer Allied Spec

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Abstract Introduction: Multiple myeloma is a hematologic malignancy characterized by the proliferation of plasma cells and typically presents with lesions in bone, known as plasmacytomas. Through hematogenous spread, extramedullary plasmacytomas can develop in soft tissue in any location of the body. This case report describes a patient with multiple myeloma who presented with an extramedullary plasmacytoma on his maxillary gingiva and provides an updated review on the classification and characterization of extramedullary plasmacytomas of the oral cavity. Case description: A 53-year-old male with a known diagnosis of multiple myeloma was referred to our clinic for evaluation of a gingival nodule, which was tender to palpation and had been present for a month. Clinical examination revealed a 1.5 cm violaceous, red nodule of the maxillary buccal attached gingiva, which did not blanch on palpation. He had a similar 1 cm, smooth, red nodule of his cutaneous skin on his left arm. Radiographic examination with within normal limits without evidence of dental or bony pathology. An incisional biopsy revealed the diagnosis of plasmacytoma, indicating relapse and progression of the patient’s multiple myeloma.Practical implications: Multiple myeloma can present in the oral cavity either as intra-bony plasmacytomas, paraskeletal plasmacytomas, or extramedullary plasmacytomas in the soft tissue. Extramedullary disease representative of hematogenous spread is concerning for high-risk disease with a poor risk prognosis.

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