Oral Florid Papillomatosis Complicated by Verrucous Squamous Carcinoma

Oral florid papillomatosis in the course of lichen planus

“…The stratum granulosum is invariably absent. Samitz, Ackerman & Lantis (1967), Samitz & Weinberg (1969), Kanee (1969) and Degos et al (1970) regard OFP as a premalignant lesion, eventually turning into a verrucose squamous cell epithelioma of low-grade malignancy.…”

Human Papillomavirus‐Induced Verrucous Carcinoma of the Mouth

“…There are several references in the literature reporting successful treatment of oral verrucous carcinoma. They include: Bleomycin intraarterially, 19 or by local injection 12 ; Methotrexate in low doses or tumoricidal doses 9,20 ; cryotherapy 11,12,21 ; and carbon dioxide laser therapy 22 . Radiation therapy is also an option, although anaplastic transformation has been reported shortly after radiation therapy, 23 other cases have been successfully treated 24…”

Condyloma acuminatum: Epidemiological, clinical and therapeutic aspects

“…Condyloma a c u m i n a t u m has been associated with carcinoma of the penis (53) and less commonly with carcinomas of the ureters, urethera, bladder (38,41,66) and m o u t h (37). In addition, the Buschke-L/Swenstein giant condyloma is feR to represent a low grade verrucous squamous cell carcinoma, b u t it rarely metastasizes (8).…”