Oral Focal Mucinosis of the Tongue: A Rare Clinical Case

Pacifici, L; Meleo, Deborah; Pompa, Giorgio; Pacifici, Andrea; Gambarini, Gianluca; Testarelli, Luca

doi:10.1177/1721727x1201000113

Cited by 5 publications

(3 citation statements)

References 19 publications

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“…It has been reported that, in cancer patients, IL-l~and IL-6 are associated with clinical features of the cachectic condition, such as weakness, loss of appetite, weight loss and sarcopenia (82)(83)(84)(85)(86)(87). Several studies have shown an association between dietary factors and the incidence of cancer.…”

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confidence: 99%

Nutrition and Cancer Prevention

Tetè

Nicoletti

Saggini

et al. 2012

Int J Immunopathol Pharmacol

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Cancer cells invade surrounding tissues and metastasize to distant sites. Diet high in fat is a strong link to, and perhaps causes, a high incidence of tumours. Trans-fatty acid might impair the function and it could be involved in the development of cancer. Cholesterol is also strongly suspected to be involved in the development of tumours, therefore it is important for everyone to eat well, especially for people with cancer to prevent the body tissues from breaking down and helping to rebuild the normal tissue that may have been affected by the treatments. Factors secreted by adipocytes and macrophages such as TNF-alpha and other inflammatory proteins are involved in inflammation in cancer. In addition, MCSF which up-regulates adipocyte tissue is also important for the stimulation of fat cell proliferation and is expressed by human adipocytes. Many cytokines, such as IL-1, IL-6, IL-8, IL-32, IL-33 and MCP-1, are biomarkers for cancer and chronic diseases along with transcription factors NFκB and AP-1; these last two factors are important bioactive substances on the molecular mechanism of the control of genes which in turn affect cellular metabolism. In this paper we revisit the interrelationship between cancer and metabolism.

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confidence: 99%

Nutrition and Cancer Prevention

Tetè

Nicoletti

Saggini

et al. 2012

Int J Immunopathol Pharmacol

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“…OFM develops following an excessive secretion of hyaluronic acid and mucoid accumulation between collagen fibers. Ultimately, hyaluronic acid replaces collagen fibers [28][29][30][31]. OFM occurs predominantly in adults during the fourth and fifth decades of life [8].…”

Section: Discussionmentioning

confidence: 99%

Oral Focal Mucinosis: A Case Report and Literature Review

Agha‐Hosseini¹,

Sadrzadeh-Afshar

2018

J Islam Dent Assoc Iran

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Introduction: Oral focal mucinosis (OFM) is the soft tissue counterpart of cutaneous focal mucinosis (CFM) and is often misdiagnosed as an oral myxoma. OFM occurs during the fourth and fifth decades of life, predominantly in women (two females per male). Case Report: A 22-year-old lactating female presented with a growing painless, sessile tumor with pale pink color and a lobulated surface with ulcers at the depths of interlobular fissures in the premolar-molar area of the left mandibular alveolar ridge, dating back one year. The tumor was completely excised. No recurrence was observed during the follow-ups over the next three years. Conclusion: The current case appears to be the only one with an OFM reported during the breastfeeding period; therefore, the role of hormonal factors in the pathogenesis of the lesion should be taken into consideration.

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“…Nerve sheath myxoma or neurothekeoma has abundant alcianophilic content, numerous mast cells, cells positive for S-100 protein and lobular aspect, differing from the lesion in question. In the same way, it is possible to distinguish OFM from neurofibroma with myxomatous areas [1,12]. Therefore, a routine histological analysis may not always establish the diagnosis of these lesions, due to the similarities among them [10], and complementary histochemical or immunohistochemical analysis is necessary in some cases.…”

Section: Discussionmentioning

confidence: 99%

Oral focal mucinosis: review of the literature and two case reports

Achkar

Machado²,

Almeida³

et al. 2016

Dermatology Online Journal

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Oral focal mucinosis is a rare condition, clinically characterized by an asymptomatic swelling, without distinct, specific features, which occurs predominantly in adults of the female gender. Its clinical aspect leads to various differential diagnoses, and final diagnosis is only possible by means of histopathological exam, in which a well-delimited myxomatous area containing mucinous material is observed. In the present study, a review of the English-language literature about the lesion, was conducted, covering the period from 1974 to March 2015. We report two new cases, thereby contributing to the knowledge and differential diagnosis of this entity.

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Oral Focal Mucinosis of the Tongue: A Rare Clinical Case

Cited by 5 publications

References 19 publications

Nutrition and Cancer Prevention

Nutrition and Cancer Prevention

Oral Focal Mucinosis: A Case Report and Literature Review

Oral focal mucinosis: review of the literature and two case reports

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