Oral Health, Temporomandibular Disorder, and Masticatory Performance in Patients with Charcot‐Marie‐Tooth Type 2

Abstract

Background. The aim of this study was to evaluate the oral health status of temporomandibular disorders (TMD) and bruxism, as well as to measure masticatory performance of subjects with Charcot-Marie-Tooth type 2 (CMT2). Methods and Results. The average number of decayed, missing, and filled teeth (DMFT) for both groups, control (CG) and CMT2, was considered low (CG = 2.46; CMT2 = 1.85, P = 0.227). The OHIP-14 score was considered low (CG = 2.86, CMT2 = 5.83, P = 0.899). The prevalence of self-reported TMD was 33.3% and 38.9% (P = 0.718) in CG and CMT2 respectively and for self-reported bruxism was 4.8% (CG) and 22.2% (CMT2), without significant difference between groups (P = 0.162). The most common clinical sign of TMD was masseter (CG = 38.1%; CMT2 = 66.7%) and temporalis (CG = 19.0%; GCMT2 = 33.3%) muscle pain. The geometric mean diameter (GMD) was not significantly different between groups (CG = 4369; CMT2 = 4627, P = 0.157). Conclusion. We conclude that the CMT2 disease did not negatively have influence either on oral health status in the presence and severity of TMD and bruxism or on masticatory performance.

Sleep Pattern in Charcot-Marie-Tooth Disease Type 2: Report of Family Case Series

“…32 Also, the absence of sleep bruxism in the PSG corroborates a previous study in this same family, in which the subjective complaint of clenching teeth associated with orofacial pain was not observed. 35 In the sleep architecture, our study showed no important changes in sleep latency, although most patients reported difficulty in initiating sleep in the PSQI questionnaire. However, there was an increase of WASO (%) and arousals, suggesting a fragmented sleep pattern, contributing to the lower sleep efficiency (< 85%) found in 50% of the patients.…”

Salivary Biomarkers and Temporomandibular Disorders: A Systematic Review conducted according to PRISMA guidelines and the Cochrane Handbook for Systematic Reviews of Interventions

“…Acidic environments can trigger enamel demineralization, which might result in dental issues and worsen TMD symptoms. 23 Cortisol and other stress-related indicators can be found in saliva. For those who are sensitive, chronic stress and its effects on saliva composition may affect muscle tension and exacerbate the symptoms of TMD.…”

“…The oral environment may change as a result of pH and buffering capacity changes in saliva. Acidic environments can trigger enamel demineralization, which might result in dental issues and worsen TMD symptoms 23 . Cortisol and other stress‐related indicators can be found in saliva.…”