Oral Human Papillomavirus in Youth From the Pediatric HIV/AIDS Cohort Study

Abstract

In contrast to high rates of oral HPV found in HIV-infected adults, only 2% of 209 perinatally HIV-infected youth had oral HPV. This rate was similar in HIV exposed but uninfected youth. No association was found with sexual activity; however, low CD4 counts were associated with oral HPV.

Current trends and new developments in HIV research and periodontal diseases

“…[100][101][102][103] In addition, the persistence of human papillomavirus was demonstrated in the recent Pediatric HIV/AIDS Cohort Study, where human papillomavirus infection was associated with lower CD4 levels. 104 Therefore, as in…”

“…In several studies conducted in the combined antiretroviral therapies era, detection rates for oral human papillomavirus ranged from 14% to 37% for people with HIV to < 10% for people without HIV . In addition, the persistence of human papillomavirus was demonstrated in the recent Pediatric HIV/AIDS Cohort Study, where human papillomavirus infection was associated with lower CD4 levels . Therefore, as in studies of the bacterial microbiome, direct or indirect effects of combined antiretroviral therapies in altering the viral microbiome may have both beneficial and detrimental effects.…”

“…[100][101][102][103] In addition, the persistence of human papillomavirus was demonstrated in the recent Pediatric HIV/AIDS Cohort Study, where human papillomavirus infection was associated with lower CD4 levels. 104 Therefore, as in F I G U R E 5 Single human papillomavirus wart on upper right labial mucosa studies of the bacterial microbiome, direct or indirect effects of combined antiretroviral therapies in altering the viral microbiome may have both beneficial and detrimental effects.…”