Oral hypoglycaemic, antihyperglycaemic and antidiabetic activities of Sri Lankan Broken Orange Pekoe Fannings (BOPF) grade black tea (Camellia sinensis L.) in rats

Abeywickrama, K.R.W.; Ratnasooriya, W. D.; Amarakoon, A.M.T.

doi:10.1016/j.jep.2011.02.035

Cited by 59 publications

(32 citation statements)

References 30 publications

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“…Our previous studies have shown that Sri Lankan black tea has both hypoglycaemic [15,16] and anti-diabetic [15,16] activities. These activities would be an additional advantage in consuming black tea since hyperglycaemia promotes AGEs formation [1][2][3][4][5].…”

Section: Resultsmentioning

confidence: 99%

In vitro Antiglycation and Cross-Link Breaking Activities of Sri Lankan Low-Grown Orthodox Orange Pekoe Grade Black Tea (Camellia sinensis L)

Ratnasooriya¹,

Abeysekera²,

Muthunayake³

et al. 2014

Trop. J. Pharm Res

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Section: Resultsmentioning

confidence: 99%

In vitro Antiglycation and Cross-Link Breaking Activities of Sri Lankan Low-Grown Orthodox Orange Pekoe Grade Black Tea (Camellia sinensis L)

Ratnasooriya¹,

Abeysekera²,

Muthunayake³

et al. 2014

Trop. J. Pharm Res

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“…Some authors have suggested an increased catabolism of glucose due to glucose transporter type 4 translocation to the plasma membrane in muscle and brown adipose cells [16] with up-regulation of the uncoupling protein-1 in brown adipose tissue and hepatic gluconeogenesis [15,17] occurring as a result of hyperinsulinemia or the enhancement of peripheral glucose utilization [16,18] as plausible mechanisms of action. Moreover, a possible stimulatory mechanism on the few surviving β -cells has been considered, which could allow the release of more insulin [19] . Additionally, the consumption of herb extracts in diabetic rats reduced blood glucose levels and increased glucose tolerance not only by promoting insulin sensitivity but also by reversed activity of hepatic enzymes (glycogen synthetase) in diabetic rats near the normal levels, through mechanisms that involve gluconeogenesis [20] or the release of somatomedin having insulin-like activity or inhibition of glucagon release [21] .…”

Section: Treatmentmentioning

confidence: 99%

Morphological changes in the pancreas and glucose reduction of the aqueous extract of Costus afer leaf on alloxan-induced diabetic rats

Ezejiofor

Orish

Orisakwe

2014

Journal of Basic and Clinical Physiology and Pharmacology

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“…Os chás produzidos a partir da infusão de suas folhas e brotos constituem uma das bebidas mais consumidas no mundo (Lima et al, 2009), sendo consideradas alimentos funcionais e fitoterápicos, por conterem variados compostos do metabolismo secundário com propriedades medicinais (Abeywickrama et al, 2011), tais como, polifenóis, catequinas, cafeína, teanina, saponina (Ma & Chen, 2007).…”

Section: Introductionunclassified

Enraizamento de estacas de genótipos de Camellia sinensis L. em meio ácido, presença de alumínio e ácido indolbutírico

Lima

Moraes

Silva

2016

Rev. bras. plantas med.

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RESUMO:Experimentos foram conduzidos para avaliar o efeito do meio ácido e do alumínio, assim como para determinar a concentração mais apropriada de ácido indolbutírico (AIB) para o enraizamento de estacas de diferentes genótipos de Camellia sinensis L (planta de chá). Para tal, foram coletados ramos de plantas-matrizes em Pariquera-Açu-SP, Brasil, no inverno de 2012 e preparadas estacas semi-lenhosas, contendo uma gema e uma folha, que foram manti das em viveiro com 70% de sombreamento. A irrigação do substrato foi feita com água e soluções contendo ácido fosfórico e sulfato de alumínio a pH 5,5, 4,5; 3,5. No primeiro experimento, o delineamento experimental foi o inteiramente casualizado em esquema fatorial 3 x 7, três genótipos (F 15, IAC 259 e Comum) e sete condições diferentes de enraizamento (vermiculita a pH 6,5, vermiculita acidificada com ácido fosfórico a pH 3,5; 4,5 e 5,5 ou vermiculita acidificada com sulfato de alumínio a pH 3,5; 4,5 e 5,5). No segundo experimento, o tratamento que promoveu o maior enraizamento no primeiro experimento (vermiculita acidificada com sulfato de alumínio a pH 3,5) foi combinado ao tratamento com AIB. O delineamento experimental utilizado foi o inteiramente casualizado em esquema fatorial 3 x 6, sendo três genótipos e seis concentrações de AIB (0, 2000, 4000, 6000, 8000 e 1000 mg L -1 ). A vermiculita acidificada com sulfato de alumínio a pH 3,5, combinada a aplicação de 10000 mg L -1 de AIB por 30 segundos, foi o tratamento mais adequado para o enraizamento de estacas semi-lenhosas dos genótipos F15, IAC 259 e Comum.Palavras-chave: planta de chá, propagação vegetativa, acidificação, auxina.ABSTRACT: Rooting of Camellia sinensis L. in acid medium, the presence of aluminum and indolebutyric acid. The experiments were carried out to evaluate the effect of medium acidic and aluminum, as well as determine the most suitable concentration of indolebutyric acid (IBA) for rooting cuttings of different genotypes of Camellia sinensis L (tea plant). Such, stems were collected from mother plants in Pariquera-Açu, São Paulo state, Brazil, in winter 2012 and prepared semi-hardwood cuttings, with one bud and one leaf, which were kept in a nursery with 70% of shading. Irrigation substrate was taken with water and solutions containing phosphoric acid and aluminum sulfate at pH 5.5, 4.5; 3,5. In the first experiment, the experimental design was completely randomized in a factorial scheme 3x7, three genotypes (F 15, IAC 259 and Comum) and seven different conditions of rooting (vermiculite at pH 6.5, acidified with phosphoric acid or aluminum sulfate vermiculite at pH 3.5, 4.5 and 5.5). In the second experiment, the treatment that promoted the highest rooting in the first experiment (vermiculite acidified with aluminum sulfate at pH 3.5) was combined with treatment with IBA The experimental design was completely randomized in a factorial scheme 3x6, three genotypes and six concentrations of IBA (0, 2.000, 4.000, 6.000, 8.000 and 10.000 mg L -1 ). Vermiculite acidified with aluminum sulphate ...

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Oral hypoglycaemic, antihyperglycaemic and antidiabetic activities of Sri Lankan Broken Orange Pekoe Fannings (BOPF) grade black tea (Camellia sinensis L.) in rats

Cited by 59 publications

References 30 publications

<i>In vitro</i> Antiglycation and Cross-Link Breaking Activities of Sri Lankan Low-Grown Orthodox Orange Pekoe Grade Black Tea (<i>Camellia sinensis</i> L)

<i>In vitro</i> Antiglycation and Cross-Link Breaking Activities of Sri Lankan Low-Grown Orthodox Orange Pekoe Grade Black Tea (<i>Camellia sinensis</i> L)

Morphological changes in the pancreas and glucose reduction of the aqueous extract of Costus afer leaf on alloxan-induced diabetic rats

Enraizamento de estacas de genótipos de Camellia sinensis L. em meio ácido, presença de alumínio e ácido indolbutírico

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