Oral Lichen Planus and Allergy to Dental Amalgam Restorations

Laeijendecker, Ronald; Dekker, Sybren K.; Burger, Piet M.; Mulder, Paul; Joost, Theodoor van; Neumann, Martino

doi:10.1001/archderm.140.12.1434

Cited by 108 publications

(79 citation statements)

References 32 publications

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“…6,7 Amalgam was also said to cause oral lichenoid drug reactions, although these lesions were quite uncommon. 8 Amalgam use in dentistry has been embroiled in controversy for the past 3 decades, which has led to widely differing strategies. Scandinavian countries have begun to phase out the use of amalgams completely.…”

Section: Introductionmentioning

confidence: 99%

Perception of Patients with Amalgam Fillings about Toxicity of Mercury in Dental Amalgam

Bamise

Oginni²,

Adedigba³

et al. 2012

The Journal of Contemporary Dental Practice

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Objective The objective of this study is to evaluate the awareness of patients with dental fillings about the toxicity of mercury in dental amalgam. Materials and methods Adult patients having at least one amalgam filling in their mouth were recruited in the Oral Diagnosis Department of OAUTHC, Ile-Ife Dental Hospital. Participants were recruited consecutively as they report in the clinic. Data were collected using a structured questionnaire developed based on standard questions from relevant publications. They were asked to indicate the type of filling material in their mouth, ingredients of the material, previous knowledge of mercury in dental amalgam and ailments due to mercury. They were to indicate their level of agreement with filling their cavities with dental amalgam despite prior information about its mercury content. Results There were about 446 respondents analyzed; male, 194 (43.5%); female 252 (56.5%). Six (1.4%) and 21 (4.7%) respondents were primary and secondary schools students respectively; 15(3.4%) had no formal education while about 410 (91.9%) were either undergraduate or graduate. All of them had at least one amalgam filling. 249 (55%) participants know the type of filling on their teeth; 156 (34.5%) had the knowledge of the presence of mercury in dental amalgam while 26.1% believed mercury can cause problems in human beings. About 90 (19.9%) participants claimed to have heard about adverse reactions to dental amalgams and 34 (7.5%) of them have heard about people recovering from an illness after removal of their filling. The level of agreement with filling their cavities with amalgam despite prior knowledge of its mercury content was 74% while 60% was observed for allowing just any material to be placed on their teeth. Conclusion Awareness of toxicity of mercury in dental amalgam was slightly low among the respondents studied. This may be suggested to be a reflection of nonexistent of global amalgam controversy in Nigeria. How to cite this article Bamise CT, Oginni AO, Adedigba MA, Olagundoye OO. Perception of Patients with Amalgam Fillings about Toxicity of Mercury in Dental Amalgam. J Contemp Dent Pract 2012;13(3):289-293.

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Section: Introductionmentioning

confidence: 99%

Perception of Patients with Amalgam Fillings about Toxicity of Mercury in Dental Amalgam

Bamise

Oginni²,

Adedigba³

et al. 2012

The Journal of Contemporary Dental Practice

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“…A more distinctive manifestation are lichenoid reactions usually localised on the buccal mucosa, tongue and lips 8,9 . These chronic changes are most often associated with long-term exposure of the oral mucosa to dental metals, and also to acrylates, composite materials, additives and other substances, which lead to the development of a delayed hypersensitivity reaction 10,11 .…”

Section: Introductionmentioning

confidence: 99%

Oral Lichenoid Lesions and Allergy to Dental Materials

Ditrichová¹,

Kaprálová²,

Tichý³

et al. 2007

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

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Background: Dental materials, oral hygiene products and food additives may cause contact allergic reactions in the mouth with varied clinical presentation. Oral lichenoid lesions (lichen planus-like lesions) can be induced by hypersensitivity to dental restorative metals, acrylates, fl avorings and other substances.Aim: The aim of this study was to demonstrate contact allergy to dental materials in patients with oral lichenoid lesions using patch tests.Patients and methods: Routine patch tests with two sets of allergens -"European Standard" and "Dental Screening" (Chemotechnique Diagnostics, Sweden) supplemented with pulverized amalgam, iridium, indium, menthol, sorbic acid and platinum were done on a set of 25 patients with lichenoid lesions located on the buccal mucosa, tongue and lips. Application and interpretation of the tests were conducted according to ICDRG (International Contact Dermatitis Research Group).Results: 15 (60 %) patients showed sensitization to 1 or more allergens, with a total of 31 positive reactions. The greatest frequency of positive reactions was to dental metals, with a total of 27 positive reactions. The order of tested metals according to frequency of positive reactions was mercury (6/25/24 %), amalgam (6/25/24 %), nickel (4/25/16 %), palladium (4/25/16 %), cobalt (3/25/12 %), gold (2/25/8 %), chrome (1/25/4 %), indium (1/25/4 %). The clinical relevance of the results with regard to the material's presence in the mouth was demonstrated in 11 (44 %) patients. In 9 patients, replacement of the positively tested materials led to healing or to signifi cant regression of mucosal changes. Conclusions:The results of the patch tests showed the possible contribution of contact sensitization in the pathogenesis of lichenoid manifestations in the oral cavity. Due to the premalignant character of these lesions, replacement of positively tested materials and follow up of these patients is advised.

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“…OLRs caused by amalgam restorations can be found in the literature, with symptoms such as eczema, urticaria, wheals on the face and limbs, rashes and sometimes pink or Kawasaki disease [2,12,23]. In several cases, systemic reactions have been noted [24].…”

Section: Discussionmentioning

confidence: 99%

“…Many dental materials and medicaments contain substances that can cause hypersensitivity reactions of the oral mucosa or the skin [1][2][3]. Generally, the allergenic substances in the dental environment are local anesthetic agents [4], antibiotics [5], restorative materials [6] and latex [7].…”

Section: Introductionmentioning

confidence: 99%