Oral Lichen Planus in a 7-year-old Child: A Rare Case Report

Chinnasamy, Nanthini K; Venugopal, Divyambika Catakapatri; Sathasivasubramanian, S; Narasimhan, Malathi

doi:10.5005/jp-journals-10005-1713

Cited by 3 publications

(2 citation statements)

References 17 publications

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“…Although OLPc was initially described in 1920s, there are few reports, and oral involvement has been often described in association with predisposing conditions, such as hepatitis and vaccination. 6,7,10,11 The frequency of OLPc is unknown, but it is thought to be higher in Asians 11,12 suggesting a genetic susceptibility, which could contribute to the high occurrence of LP in Asians. 7,10 Several case studies have shown that a family history of lichen planus in children is unusual, occurring in only 1%-2% of cases.…”

Section: Discussionmentioning

confidence: 99%

Oral lichen planus in children: An Italian case series

Spirito

Caponio

Muzio

et al. 2023

Pediatric Dermatology

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Oral lichen planus usually occurs in adults; there are no clear data regarding the incidence and the clinical features of oral lichen planus in children. This paper reports clinical findings, treatments, and outcomes of 13 Italian patients with oral lichen planus in childhood diagnosed between 2001 and 2021. The most common finding was keratotic lesions with reticular or papular/plaque-like patterns, confined to the tongue in seven patients. Although oral lichen planus in childhood is rare and the malignant transformation index is unknown, specialists must be aware of its characteristics and oral mucosal lesions must be correctly diagnosed and managed. K E Y W O R D S case series, childhood, lichen ruber planus, oral lichen planus, pediatric oral lichen planus 1 | INTRODUCTION Lichen planus (LP) is an autoimmune chronic inflammatory disorder affecting the skin and mucous membranes in which autocytotoxic Tlymphocytes trigger apoptosis of epithelial cells. 1 The clinical features of oral lichen planus (OLP) are varied and six different patterns occur: reticular, plaque-like, atrophic, papular, erosive, and bullous. 1 The etiology remains unclear and related to several potential local and systemic triggers that activate T cell-mediated auto-cytotoxicity.OLP usually occurs in the fourth decade with a prevalence rate of 0.1%-2.2%, with a female-to-male ratio of 1.4:1. 1 There are no clear data regarding the incidence of OLP in children (OLPc), although according to some authors the prevalence in children is <2%-3% of total cases. According to a recent systematic review, the oral mucosa is involved in 22% of pediatric patients, compared to 30%-70% of adult patients. 2 The low incidence of OLPc seems to be related to factors such as low incidence of systemic and autoimmune diseases, low levels of stress (considered a exacerbation trigger factor in adults), less usage of amalgam and orthodontic materials, which were recognized precipitating factors 3,4 in adults, as well as no tobacco consumption, which is a known risk factor for oral LP, 5 and fewer symptoms, leading to a number of undiagnosed cases. [6][7][8][9] This study reports clinical

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Section: Discussionmentioning

confidence: 99%

Oral lichen planus in children: An Italian case series

Spirito

Caponio

Muzio

et al. 2023

Pediatric Dermatology

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“…Oral lichen planus (OLP) generally affects patients of middle age or older (1). However, it has rarely been detected in pediatric patients (1)(2)(3)(4)(5)(6)(7)(8)(9). Like adult OLP, OLP in childhood (OLPc) is diagnosed clinically and histopathologically -but in individuals <20 years old-; after excluding oral lichenoid reaction through evidence negating mucosal contact with dental restorative materials or exposure to medications that are known to induce oral lichenoid reactions (10).…”

Section: Introductionmentioning

confidence: 99%

Çocukluk Çağında Benzersiz Histolojik Bulgusu Olan Oral Liken Planus: Olgu Sunumu

Gamal-AbdelNaser¹

2023

Düzce Tıp Fakültesi Dergisi

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Oral lichen planus is a chronic inflammatory disease that targets adults. Over the years, few reports documented solitary cases of children being affected by oral lichen planus. In this report, a case of an 8-year-old, medically uncompromised boy who complained of a severe burning sensation in the tongue with a history of one year of remission and exacerbation was presented. When examined, the tongue showed a large irregular superficial non-indurated ulcer occupying the whole anterior 2/3 of the tongue sparing the tip and was surrounded by white radiating lines. The ulcerative lesion showed a peculiar butterfly pattern. Histopathological examination of the incisional biopsy showed intraepithelial civatte bodies and dense subepithelial lymphocytic infiltrate arranged in a pseudo-lymphomatous shape. Although the clinical and histological pictures suggest lichen planus, the atypical arrangement of lymphocytes brought up a question mark. This report demonstrates a peculiar clinical picture of a rare disease combined with a unique histopathologic finding.

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