Oral Linear Epidermal Nevus: A Review of the Literature and Report of Two New Cases

Tesi, D.; Ficarra, Giuseppe

doi:10.1007/s12105-010-0165-7

Cited by 14 publications

(16 citation statements)

References 16 publications

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“…Lastly, verrucous epidermal nevus (VEN), a congenital malformation or hamartoma derived from embryonic ectoderm, should be also considered. Oral involvement by VEN is a rare manifestation, described as unilateral or midline papules or nodules, with a papillary or verrucous surface, usually affecting the tongue, lips, gingiva, buccal mucosa and palate [18].…”

Section: Discussionmentioning

confidence: 99%

Glycogenic acanthosis on mouth clinically present as white plaque

Schulz

Biancardi

Fernandes

et al. 2018

RGO, Rev. Gaúch. Odontol.

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Glycogenic acanthosis is a benign condition, commonly observed during endoscopic procedures in older patients, which present as slightly elevated whitish plaques often on the lower third of the oesophagus. Microscopically, glycogenic acanthosis is composed of hyperplastic squamous epithelium with intracytoplasmic glycogen deposits. The extraoesophageal glycogenic acanthosis is extremely rare, with only three case reports in the English-language literature. We report a white lesion showing glycogenic acanthosis-like features located on the left posterolateral border of the tongue, affecting a 56-year-old male patient. The medical history was non-contributory and the patient did not show any lesions during endoscopic examination of the oesophagus, stomach, and upper duodenum. Glycogenic acanthosis is a benign condition, which should be included in the differential diagnosis when assessing oral white lesions. It is important also to recognize this benign condition early and rule out the possibility of other more severe diseases, but further studies were necessary for better define their potential for persistence or recurrence, as observed in the current case.

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Section: Discussionmentioning

confidence: 99%

Glycogenic acanthosis on mouth clinically present as white plaque

Schulz

Biancardi

Fernandes

et al. 2018

RGO, Rev. Gaúch. Odontol.

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“…More rarely, ILVEN has been described on the trunk with typical curvilinear transverse bands, which follow the Blaschko lines, sometimes stopping at the midline [ 8 ]. Different localisations, like genital or mucosal, are extremely rare [ 9 - 11 ].…”

Section: Discussionmentioning

confidence: 99%

A Case of “Inflammatory Linear Verrucous Epidermal Nevus” (ILVEN) Treated with CO2 Laser Ablation

Gianfaldoni¹,

Tchernev²,

Gianfaldoni³

et al. 2017

Open Access Maced J Med Sci

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The “inflammatory linear verrucous epidermal nevus” is a rare disease, consisting of hyperplasia of the normal components of the epidermis. Its clinical features include erythematous and hyperkeratosic, warty, sometimes psoriasiform or lichenoid patches with a typical linear arrangement. At present, there are no effective medical therapies available. Currently, the best therapeutic results are obtained with surgical excision or the latest laser therapy. The Authors present a 9-years old girl with an inflammatory linear verrucous epidermal nevus on her neck, successfully treated with CO2 Laser ablation.

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“…24,25 Oral LEN has been successfully treated with surgical excision quite often without recurrence. 4 Treatment of cutaneous LEN includes both topical and surgical modalities. Topical calcipotriol has reportedly shown partial regression and growth retardation of lesions.…”

Section: Discussionmentioning

confidence: 99%

“…LEN differs from a nevus that presents as a solitary mass and is considered its own distinct form of nevus. 1,4 The lines of Blaschko, although not fully understood, are believed to represent the pathway of migrating embryonic skin cells. LEN represents a form of mosaicism, whereby an individual has cells with different genotypes derived from the same zygote.…”

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confidence: 99%